The comparison of the effects of nano-silymarin and silymarin on high-fat diet-induced fatty liver of adult male rats [PDF]
Objective: Considering the high prevalence of non-alcoholic fatty liver disease and its complications, this study aims to determine and compare the effect of nano-silymarin and silymarin on non-alcoholic fatty liver in rats.Materials and Methods: Rats ...
Reza Mohebbati +6 more
doaj +1 more source
Silymarin protects liver against toxic effects of anti-tuberculosis drugs in experimental animals [PDF]
Background The first line anti-tuberculosis drugs isoniazid (INH), rifampicin (RIF) and pyrazinamide (PZA) continues to be the effective drugs in the treatment of tuberculosis, however, the use of these drugs is associated with toxic reactions in tissues,
Sude Eminzade +32 more
core +1 more source
Silymarin and diabetic nephropathy.
Nephropathy is one of the most important complications of diabetes mellitus and drug induced toxicity. Nephrotoxicity is mostly related to oxidative stress and nowadays much attention has been made towards the possible kidney protective properties of medicinal plants. Studies revealed, silymarin is useful for diabetic nephropathy.
Rafieian-Kopaie, Mahmoud, Nasri, Hamid
openaire +2 more sources
Identification of hepatoprotective flavonolignans from silymarin [PDF]
Silymarin, also known as milk thistle extract, inhibits hepatitis C virus (HCV) infection and also displays antioxidant, anti-inflammatory, and immunomodulatory actions that contribute to its hepatoprotective effects. In the current study, we evaluated the hepatoprotective actions of the seven major flavonolignans and one flavonoid that comprise ...
Stephen J, Polyak +7 more
openaire +2 more sources
Hepatoprotective effects of silymarin on CCl4-induced hepatic damage in broiler chickens model
This study was conducted to investigate the hepatoprotective effects of silymarin on CCl4-induced oxidative stress in broiler chickens model. A total of 240 day-old broilers were divided into 4 equal groups (n = 60) composed of a control group (receiving
A. Baradaran +3 more
doaj +1 more source
Ultrasonic-assisted enzymatic extraction of silymarin from the Silybum marianum seed shell and evaluation of its antioxidant activity in vitro [PDF]
This study revealed the optimal conditions for the Ultrasonic-Assisted Enzymatic Extraction (UAEE) of silymarin, and include: the concentration of ethanol, 50 %; enzyme concentration, 30 U/mg; liquid-solid ratio, 6:1; an extraction time of 120 min; and ...
Li, XinHua, Zhao, Fei
core +1 more source
Analgesic effect of silymarin in chicks [PDF]
There were no studies about the analgesic effect of silymarin in the chicken. This study examined antinociceptive effect of silymarin given intraperitonially in 7-9 day-old chicks.
Ahmed Salah Naser, yasser albadrany
doaj +1 more source
Hepatoprotective effect of silymarin
The use of medicinal plants in treating illnesses has been reported since ancestral times. In the case of hepatic diseases, several species such as Silybum marianum, Phyllanthus niruri, and Panus giganteus (Berk.) have been shown to ameliorate hepatic lesions.
Nancy, Vargas-Mendoza +7 more
openaire +2 more sources
Pengaruh Cara Ekstraksi Terhadap Kadar Sari Dan Kadar Sylimarin Dalam Biji Silybum Marianum (L.) Gaertn. [PDF]
Silybum marianum (L.) Gaertn.atau dikenal dengan nama milk thistle digunakan dalam pengobatan hepatitis kronik dan akut serta sirosis yang disebabkan alkohol, obat-obatan maupun racun.
M. Sholikhah, Ika Yanti +1 more
core +2 more sources
The Impact of Silymarin on Improvement of Hepatic Abnormalities in Patients with Severe Preeclampsia: A Randomized Clinical Trial [PDF]
Background: Preeclampsia is a pregnancy-specific disorder, associated with increased blood pressure and proteinuria, and in extreme cases it can also cause liver and kidney problems. Objective: To determine the impact of silymarin on the improvement of
Kaveh Baghbahadorani, F., Miraj, S.
core +1 more source

