Results 91 to 100 of about 469 (114)

The Efficacy and Safety of Levosimendan in Patients with Advanced Heart Failure: An Updated Meta-Analysis of Randomized Controlled Trials. [PDF]

open access: yesAm J Cardiovasc Drugs
Elsaeidy AS   +10 more
europepmc   +1 more source

Linee guida ESC per la diagnosi e il trattamento dello scompenso cardiaco acuto e cronico 2008 = Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008 [PDF]

open access: yes, 2009
Atar, D.   +14 more
core  

The favourable alliance between CardioMEMS and levosimendan in patients with advanced heart failure. [PDF]

open access: yesESC Heart Fail
Visco V   +11 more
europepmc   +1 more source

Enantiomeric analysis of simendan on polysaccharide‐based stationary phases by polar organic solvent chromatography

open access: closedJournal of Separation Science, 2020
AbstractHerein, the enantiomeric separation of simendan by high‐performance liquid chromatography with ultraviolet detection using polysaccharide‐based chiral stationary phases in polar organic mode is described. Three chiral columns (Chiralpak AD‐H, Chiralcel OD‐H, and Chiralpak AS) were screened using pure methanol and acetonitrile without additives ...
Lingping Cheng   +3 more
openaire   +3 more sources

Enantiomeric bioanalysis of simendan and levosimendan by chiral high-performance liquid chromatography

open access: closedChirality, 1996
rac-Simendan, (+/-)-(R,S)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)-phenyl ] hydrazono]propanedinitrile, and the levorotatory enantiomer levosimendan, are drug candidates intended for the treatment of congestive heart failure. An enantiospecific high-performance liquid chromatographic (HPLC) method suitable for determination of the ratio of
T, Wikberg, T, Korkolainen, M, Karlsson
openaire   +3 more sources

Pharmacokinetics and pharmacodynamics of simendan, a novel calcium sensitizer, in healthy volunteers

open access: closedClinical Pharmacology and Therapeutics, 1994
To assess pharmacokinetics and correlation of pharmacokinetics and pharmacodynamics of simendan, a new calcium-sensitizing compound aimed at the treatment of congestive heart failure, in healthy volunteers.Simendan was administered to eight healthy subjects in seven different doses, and its concentrations in plasma and proportions of enantiomers ...
J, Lilleberg   +4 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy