Results 221 to 230 of about 1,252,233 (299)
Structure characterization with NMR molecular networking. [PDF]
Stienstra CMK +10 more
europepmc +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
DDI-AttendNet: cross attention with structured graph learning for inter-drug connectivity analysis. [PDF]
Wang J, Du H, Li Y.
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Benchmarking methods for measuring biosynthetic gene cluster similarity and determination of gene cluster families. [PDF]
Oyedele AS, Walker AS.
europepmc +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Linking hierarchical classification of transcription factors by the structure of their DNA-binding domains to the variability of their binding site motifs. [PDF]
Levitsky VG, Vatolina TY, Raditsa VV.
europepmc +1 more source

