Results 101 to 110 of about 1,583,595 (288)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Dynamic Time Warping as a Similarity Measure: Applications in Finance [PDF]
, 2014 This paper presents the basic DTW-algorithm and the manner it can be used as a similarity measure for two different series that might differ in length. Through a simulation process it is being showed the relation of DTW-based similarity measure, dubbed ...
Alexandridis, Antonis +3 more
core
Journal of Chemical Information and ModelingThe rapid adoption of big data, machine learning (ML), and generative artificial intelligence (AI) in chemical discovery has heightened the importance of quantifying molecular similarity. Molecular similarity, commonly assessed as the distance between molecular fingerprints, is integral to applications such as database curation, diversity analysis, and
Rebekah Duke +3 more
openaire +2 more sources
Measuring Global Similarity Between Texts [PDF]
, 2014 We propose a new similarity measure between texts which, contrary to the current state-of-the-art approaches, takes a global view of the texts to be compared. We have implemented a tool to compute our textual distance and conducted experiments on several corpuses of texts.
Fahrenberg, Uli +5 more
openaire +3 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Discrete Applied Mathematics, 2003 Following the approach of Tversky's contrast model, similarity measures are introduced as order-preserving maps from specific ordered sets into the non-negative reals. The analysis of this class of functions gives rise to the definition of additive similarity measures that induce a matroid on their domain. Here the author gives a representation of this
openaire +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Policy Similarity Measure for Two-Player Zero-Sum Games
Applied SciencesPolicy space response oracles (PSRO) is an important algorithmic framework for approximating Nash equilibria in two-player zero-sum games. Enhancing policy diversity has been shown to improve the performance of PSRO in this approximation process ...
Hongsong Tang, Liuyu Xiang, Zhaofeng He
doaj +1 more source
A New Mutual Information based Similarity Measure for Medical Image Registration [PDF]
, 2012 Medical image registration (IR) is the systematic process of aligning spate images, often involving different modalities with common reference framework, so complementary information can be combined and compared.
Dooley, Laurence S. +2 more
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source