Results 101 to 110 of about 439,963 (309)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Policy Similarity Measure for Two-Player Zero-Sum Games
Applied SciencesPolicy space response oracles (PSRO) is an important algorithmic framework for approximating Nash equilibria in two-player zero-sum games. Enhancing policy diversity has been shown to improve the performance of PSRO in this approximation process ...
Hongsong Tang, Liuyu Xiang, Zhaofeng He
doaj +1 more source
Network Similarity Measure and Ediz Eccentric Connectivity Index
Complexity, 2020 Network similarity measures have proven essential in the field of network analysis. Also, topological indices have been used to quantify the topology of networks and have been well studied.
Guihai Yu, Xinzhuang Chen
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Detection of Moving Objects in Video Using a Robust
, 2007 This correspondence deals with the segmentation of a video clip into independently moving visual objects. This is an important step in structuring video data for storage in digital libraries. The method follows a bottom-up approach.
Motion Similarity Measure +1 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Text categorization and similarity analysis: similarity measure, architecture and design
, 2013 This research looks at the most appropriate similarity measure to use for a document classification problem. The goal is to find a method that is accurate in finding both semantically and version related documents.
Heese, Ralf +2 more
core
Securely computing a similarity measure [PDF]
, 2012 The present invention relates to a method and a system of securely computing a measure of similarity for at least two sets of data. A basic idea of the present invention is to securely compare two sets of encrypted data to determine whether the two sets ...
van Dijk, M.E. +3 more
core +3 more sources