Results 121 to 130 of about 3,421,730 (304)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

LCSk: A refined similarity measure

open access: yesTheoretical Computer Science, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Gary Benson   +4 more
openaire   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Clustering with Multiviewpoint-Based Similarity Measure

open access: yes, 2012
All clustering methods have to assume some cluster relationship among the data objects that they are applied on. Similarity between a pair of objects can be defined either explicitly or implicitly. In this paper, we introduce a novel multiviewpoint-based
Nguyen, Duc Thang   +5 more
core   +1 more source

Neutrosophic Refined Similarity Measure Based on Cosine Function [PDF]

open access: yes, 2014
In this paper, the cosine similarity measure of neutrosophic refined (multi-) sets is proposed and its properties are studied. The concept of this cosine similarity measure of neutrosophic refined sets is the extension of improved cosine similarity ...
Florentin Smarandache   +3 more
core   +2 more sources

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Similarity threshold variations considering full and partial datasets (Lin’s measure).

open access: yes, 2015
This table summarizes the similarity thresholds obtained considering each complete dataset or all the groups of a dataset except one, when using Lin’s similarity measure.
Charles Bettembourg (116573)   +2 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Quantifying the informativeness of similarity measurements

open access: yesJ. Mach. Learn. Res., 2017
Summary: In this paper, we describe an unsupervised measure for quantifying the `informativeness' of correlation matrices formed from the pairwise similarities or relationships among data instances. The measure quantifies the heterogeneity of the correlations and is defined as the distance between a correlation matrix and the nearest correlation matrix
Brockmeier, Austin   +3 more
openaire   +3 more sources

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