From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
MS1Connect: a mass spectrometry run similarity measure. [PDF]
Bioinformatics, 2023 Lin A +4 more
europepmc +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A multi-dimensional fusion strategy similarity measure method for patent application technology disclosure document. [PDF]
PLoS One, 2023 Zhu M, Li M, Hou K, Wang Z, Long X.
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Tuning of controller parameters using Pythagorean fuzzy similarity measure for stable and time delayed unstable plants. [PDF]
PeerJ Comput Sci, 2023 Akdağ M, Can MS.
europepmc +1 more source
Similarity Measure and Entropy of Fuzzy Soft Sets
The Scientific World Journal, 2014 Soft set theory, proposed by Molodtsov, has been regarded as an effective mathematical tool to deal with uncertainties. Recently, uncertainty measures of soft sets and fuzzy soft sets have gained attentions from researchers.
Zhicai Liu, Keyun Qin, Zheng Pei
doaj +1 more source
Soft Similarity and Soft Cosine Measure: Similarity of Features in Vector Space Model
, 2017 We show how to consider similarity between features for calculation of similarity of objects in the Vector Space Model (VSM) for machine learning algorithms and other classes of methods that involve similarity between objects.
Gelbukh, Alexander +3 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Multi-attribute decision-making based on novel Fermatean fuzzy similarity measure and entropy measure. [PDF]
Granul Comput, 2023 Alahmadi RA +4 more
europepmc +1 more source