MS2DeepScore: a novel deep learning similarity measure to compare tandem mass spectra. [PDF]
Huber F +3 more
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Correction: Biological Characteristics of Cell Similarity Measure
Qingqing Hu +6 more
doaj +1 more source
Este estudio está enfocado en comparar diversos métodos de partición del análisis de conglomerados, usualmente conocidos como métodos no jerárquicos.
SUSANA A. LEIVA-VALDEBENITO +1 more
doaj
An Efficient Parallelized Ontology Network-Based Semantic Similarity Measure for Big Biomedical Document Clustering. [PDF]
Li M, Chen T, Ryu KH, Jin CH.
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
A New in Silico Antibody Similarity Measure Both Identifies Large Sets of Epitope Binders with Distinct CDRs and Accurately Predicts Off-Target Reactivity. [PDF]
Musnier A +14 more
europepmc +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Multicriteria group decision making via generalized trapezoidal intuitionistic fuzzy number-based novel similarity measure and its application to diverse COVID-19 scenarios. [PDF]
Dutta P, Borah G.
europepmc +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source

