Results 151 to 160 of about 1,583,050 (329)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Revista Colombiana de Estadística, 2010 This study is oriented to compare several partition methods in the context of cluster analysis, which are also called non hierarchical methods. In this work, a simulation study is performed to compare the results obtained from the implementation of the ...
Leiva-Valdebenito Susana A. +1 more
doaj
Multicriteria group decision making via generalized trapezoidal intuitionistic fuzzy number-based novel similarity measure and its application to diverse COVID-19 scenarios. [PDF]
Artif Intell Rev, 2023 Dutta P, Borah G.
europepmc +1 more source
Random Markov-self-similar measures
Stochastic Processes and their Applications, 2002 Self-similar fractal sets in the Euclidean space are usually constructed by applying iteratively a fixed finite family of contractive mappings to a given initial set. Random self-similar sets are obtained if the contractive mappings are chosen randomly and independently at each step, following a prescribed distribution.
openaire +2 more sources
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Multicriteria decision making approach using an efficient novel similarity measure for generalized trapezoidal fuzzy numbers. [PDF]
J Ambient Intell Humaniz Comput, 2023 Dutta P, Borah G.
europepmc +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Correction: Biological Characteristics of Cell Similarity Measure
Advanced Intelligent Systems, 2022 Qingqing Hu +6 more
doaj +1 more source