Results 121 to 130 of about 707,593 (286)

Diminished Signal‐to‐Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1−/y Autism Model

open access: yesAdvanced Science, EarlyView.
This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou   +7 more
wiley   +1 more source

When co-action eliminates the Simon effect: Disentangling the impact of co-actor’s presence and task sharing on joint-task performance

open access: yesFrontiers in Psychology, 2013
This study aimed at assessing whether the mere belief of performing a task with another person, who is in charge of the complementary part of the task, is sufficient for the so-called joint Simon effect to occur.
Roberta eSellaro   +3 more
doaj   +1 more source

Why are we not flooded by involuntary thoughts about the past and future? Testing the cognitive inhibition dependency hypothesis [PDF]

open access: yes, 2019
© The Author(s) 2018In everyday life, involuntary thoughts about future plans and events occur as often as involuntary thoughts about the past. However, compared to involuntary autobiographical memories (IAMs), such episodic involuntary future thoughts ...
A Beech   +88 more
core   +3 more sources

Development and Structural Characterization of UTE‐156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase

open access: yesAdvanced Science, EarlyView.
The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo   +8 more
wiley   +1 more source

The role of social cues in the deployment of spatial attention: Head-body relationships automatically activate directional spatial codes in a Simon task

open access: yesFrontiers in Integrative Neuroscience, 2012
The role of body orientation in the orienting and allocation of social attention was examined using an adapted Simon paradigm. Participants categorized the facial expression of forward facing, computer-generated human figures by pressing one of two ...
Iwona ePomianowska   +5 more
doaj   +1 more source

The Impact of Stroop Interference and the Simon Effect on Implicit Association Test Performance

open access: yes, 2018
The implicit association test (IAT) is a method used to examine associations individuals make between concepts and evaluations (Greenwald & Banaji, 1995). The typical finding with the IAT is that RTs are faster when the concepts and evaluations share the
Koch, Christopher, Meaders, Elizabeth
core  

Assessing the affective Simon paradigm as a measure of individual differences in implicit social cognition about death [PDF]

open access: yes, 2004
The authors describe the use of the affective Simon paradigm as a measure of individual differences in implicit social cognition about death. Participants made verbal responses of "good" or "bad" to death and neutral stimuli based on whether the word was
Bassett, Jonathan F.   +3 more
core  

Stimulus affective valence reverses spatial compatibility effect [PDF]

open access: yes, 2011
In spatial compatibility tasks, the Reaction Time to right-side stimuli is shorter for right key responses (compatible condition) than for left key responses (incompatible condition) and vice-versa for left-side stimuli.
CAVALLET, Mikael   +6 more
core   +1 more source

Machine‐Learning Microfluidic Minute‐Scale Microorganism Metrics Monitoring(M6)

open access: yesAdvanced Science, EarlyView.
ABSTRACT On‐site monitoring of microorganisms remains challenging because of low concentrations, strong background interference, and dynamic aerosol diffusion, particularly for aerosol‐transmitted pathogens. Here, we report a rapid detection platform that integrates a Puri‐focusing microfluidic chip, electrochemical impedance spectroscopy (EIS), and ...
Ning Yang   +14 more
wiley   +1 more source

Neural correlates of the sound facilitation effect in the modified Simon task in older adults. [PDF]

open access: yesFront Aging Neurosci, 2023
Manelis A   +4 more
europepmc   +1 more source

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