Results 101 to 110 of about 25,178,865 (330)

Basic 3-transpositions of the symplectic group Sp(2n, 2) [PDF]

open access: yesAdvances in Group Theory and Applications, 2021
Jamshid Moori
doaj   +1 more source

A WZW model based on a non-semi-simple group

open access: yes, 1993
We present a conformal field theory which desribes a homogeneous four dimensional Lorentz-signature space-time. The model is an ungauged WZW model based on a central extension of the Poincar\'e algebra.
A. A. Tseytlin   +11 more
core   +1 more source

On Ree’s series of simple groups [PDF]

open access: yesBulletin of the American Mathematical Society, 1963
Ree recently discovered a series of finite simple groups related to the simple Lie algebra of type (G2) [5; 6 ] . We have determined the irreducible characters of these groups. In this work, we do not use the actual definition of Ree's groups, but only the properties (l)-(5) given below. Since these are sufficient to determine the bulk of the character
openaire   +5 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Simple Group Choice: A minimal-information multi-criteria group decision aiding approach

open access: yesOperations Research Perspectives
In many real group decision-making problems, decisions must be made with limited data and busy Decision Makers (DMs). In such settings, asking for detailed scores or trade-off weights can be unrealistic and can obscure, rather than clarify, how a ...
River Huang
doaj   +1 more source

Quantitative characterization of finite simple groups: a complement [PDF]

open access: yesInternational Journal of Group Theory
In this paper, we summarize the research on the characterization of finite simple groups and the study of finite groups based on their ``set of element orders" and ``two orders" (the order of the group and the set of element orders). We also discuss some
Wujie Shi
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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