Results 121 to 130 of about 13,392,009 (311)

Simple Machines "50th Release" festival flier – Black Cat, Washington, D.C., December 18-20, 1994

open access: yes, 1994
Flier promoting the Simple Machines "50th Release" festival, which occurred at the Black Cat in Washington, D.C. from December 18-20, 1994. This festival featured the bands Ruby Falls, June Of '44, Secret Stars, Tuff Skool, Grenadine, Flower, The Raymond
Simple Machines
core  

Antea Group Archeologie 2017/163

open access: yes, 2020
In november 2017 heeft Antea Group een archeologisch onderzoek uitgevoerd voor het bedrijventerrein Schellevis Beton B.V. te Dussen. Eerder al is in de periode september-oktober 2016 door Antea Group voor het naastgelegen terrein een archeologisch bureau-
Sophie, Drs. G. (Antea Group)   +1 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Simple Group Choice: A minimal-information multi-criteria group decision aiding approach

open access: yesOperations Research Perspectives
In many real group decision-making problems, decisions must be made with limited data and busy Decision Makers (DMs). In such settings, asking for detailed scores or trade-off weights can be unrealistic and can obscure, rather than clarify, how a ...
River Huang
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Finite Almost Simple Groups whose Holomorph Contains a Solvable Regular Subgroup [PDF]

open access: yesAdvances in Group Theory and Applications
In our previous paper, we gave a complete list of the finite non-abelian simple groups whose holomorph contains a solvable regular subgroup. In this paper, we refine our previous work by considering all finite almost simple groups.
Cindy (Sin Yi)Tsang
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Recognition of M × M by Its Complex Group Algebra Where M Is a Simple K3-Group

open access: yesMathematics, 2018
In this paper we prove that if M is a simple K3-group, then M×M is uniquely determined by its order and some information on irreducible character degrees and as a consequence of our results we show that M×M is uniquely determined by the ...
Morteza Baniasad Azad, Behrooz Khosravi
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

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