Results 141 to 150 of about 6,369,178 (336)

On simple Shamsuddin derivations in two variables

open access: yesAnais da Academia Brasileira de Ciências
We study the subgroup of k-automorphisms of k [ x , y ] which commute with a simple derivation d of k [ x , y ]. We prove, for instance, that this subgroup is trivial when d is a shamsuddin simple derivation. in the general case of simple
RENE BALTAZAR
doaj   +1 more source

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

open access: yesFEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno   +12 more
wiley   +1 more source

ON A GROUP EXTENSION INVOLVING THE SPORADIC JANKO GROUP \(J_{2}\)

open access: yesUral Mathematical Journal
Using the electronic Atlas of Wilson [21], the group J_2 has an absolutely irreducible module of dimension 6 over F_4. Therefor a split extension group of the form 4^6:J_2:= \bar{G} exists.
Ayoub B. M. Basheer
doaj   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu   +12 more
wiley   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

open access: yesFEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li   +5 more
wiley   +1 more source

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