Results 51 to 60 of about 1,847,445 (268)
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques +5 more
wiley +1 more source
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
A characterization of Janko’s simple group [PDF]
If G is a finite group, we say that a series of subgroups G = Go > G > * > Gn= 1 is a maximal series of length n of G if Gi is a maximal subgroup of Gi1, 1 _ i < n. A subgroup H of G is called mth maximal in G if there exists at least one maximal series H= Gm< Gm.,-<
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Quasirecognition by prime graph of finite simple groups ${}^2D_n(3)$ [PDF]
Let $G$ be a finite group. In [Ghasemabadi et al., characterizations of the simple group ${}^2D_n(3)$ by prime graph and spectrum, Monatsh Math., 2011] it is proved that if $n$ is odd, then ${}^2D _n(3)$ is recognizable by prime graph and also by ...
Behrooz Khosravi , Hossein Moradi
doaj
The reduction theorem for relatively maximal subgroups
Let [Formula: see text] be a class of finite groups closed under taking subgroups, homomorphic images and extensions. It is known that if [Formula: see text] is a normal subgroup of a finite group [Formula: see text] then the image of an [Formula: see ...
Wenbin Guo +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
PEMANFAATAN METODE SAW PENDUKUNG KEPUTUSAN PENILAIAN EFEKTIVITAS MODEL PEMBELAJARAN
Students who are in junior high school should have been able to read children stories appreciative. However, based on the results of research that has been done, appreciative children's story reading skills in students is still low due to the model ...
Tri Apriyanto Sundara +1 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

