Results 61 to 70 of about 1,692,668 (268)

The effect of the use of a decision aid with individual risk estimation on the mode of delivery after a caesarean section: A prospective cohort study.

PLoS ONE, 2019
OBJECTIVE:After one previous caesarean section (CS), pregnant women can deliver by elective repeat CS or have a trial of labor which can end in a vaginal birth after caesarean (VBAC) or an unplanned CS.
Emy Vankan, Ellen Schoorel, Sander van Kuijk, Jan Nijhuis, Rosella Hermens, Hubertina Scheepers, SIMPLE study group   +6 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A Characterization of the Small Suzuki Groups by the Number of the Same Element Order [PDF]

Journal of Sciences, Islamic Republic of Iran, 2015
Suppose that  is a finite group. Then the set of all prime divisors of  is denoted by  and the set of element orders of  is denoted by . Suppose that . Then the number of elements of order  in  is denoted by  and the sizes of the set of elements with the
H. Parvizi Mosaed, A. Iranmanesh, A. Tehranian   +2 more
doaj  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Composite Higgs and leptoquarks from a simple group

Journal of High Energy Physics, 2019
We propose a composite grand unified theory to study the anomalies in the semileptonic B decays. We show a simple group containing the custodial and Standard Model gauge symmetries, that can deliver a set of composite pseudo Nambu-Goldstone bosons: the ...
Leandro Da Rold, Federico Lamagna
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

$G$-permutable Subgroups in $\operatorname{PSL}_2(q)$ and Hereditarily $G$-permutable Subgroups in $\operatorname{PSU}_3(q)$

Известия Иркутского государственного университета: Серия "Математика"
The concept of $X$-permutable subgroup, introduced by A. N. Skiba, generalizes the classical concept of a permutable subgroup. Many classes of finite groups have been characterized in terms of $X$-permutable subgroups.
A. A. Galt, V. N. Tyutyanov
doaj   +1 more source