Results 71 to 80 of about 1,361,110 (264)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
On Tensor Squares of Reducible Representations of Almost Simple Groups. II
Моделирование и анализ информационных систем, 2011 Almost simple {SM}_m -groups are considered. A group G is called {SM}_m -group if the tensor square of any irreducible representation is decomposed into the sum of all characters with multiplicities not greater than m.
S. V. Polyakov
doaj
Embeddings into left-orderable simple groups. [PDF]
J Lond Math Soc, 2022 Darbinyan A, Steenbock M.
europepmc +1 more source
Embedding rank one simple groups into rank one simple Riesz groups [PDF]
Glasgow Mathematical Journal, 2002 We give a method for embedding a large family of partially ordered simple groups of rank one into simple Riesz groups of rank one. In particular, we answer in the affirmative a question of Wehrung, by constructing a torsion-free, simple Riesz group G of rank one containing an interval D\varsubsetneqq G^+ such that 2D=G^+.
openaire +3 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
On the depth of subgroups of simple groups
Forum of Mathematics, SigmaThe depth of a subgroup H of a finite group G is a positive integer defined with respect to the inclusion of the corresponding complex group algebras $\mathbb {C}H \subseteq \mathbb {C}G$ .
Timothy C. Burness
doaj +1 more source
, 2020 The distinguishing number $D( )$ of a graph $ $ is the least size of a partition of the vertices of $ $ such that no non-trivial automorphism of $ $ preserves this partition. We show that if the automorphism group of a graph $ $ is simple, than $D( )=2$. This is obtained by establishing the distinguishing number for all possible actions of simple
Grech, Mariusz, Kisielewicz, Andrzej
openaire +2 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source