Results 81 to 90 of about 5,167,602 (281)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
On divisibility graph for simple Zassenhaus groups [PDF]
, 2014 The divisibility graph $D(G)$ for a finite group $G$ is a graph with vertex set $cs~(G)\setminus\{1\}$ where $cs~(G)$ is the set of conjugacy class sizes of $G$. Two vertices $a$ and $b$ are adjacent whenever $a$ divides $b$ or $b$ divides $a$.
A. Abdolghafourian +2 more
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
On tensor squares of irreducible representations of almost simple groups. I
Моделирование и анализ информационных систем, 2011 Almost simple SM_m-groups are considered. A group G is called a SM_m-group if the tensor square of any irreducible representation is decomposed into the sum of its irreducible representations with multiplicities not greater than m.
S. V. Polyakov
doaj
Upper bounds on the uniform spreads of the sporadic simple groups [PDF]
International Journal of Group Theory, 2019 A finite group $G$ has uniform spread $k$ if there exists a fixed conjugacy class $C$ of elements in $G$ with the property that for any $k$ nontrivial elements $s_1, s_2,ldots,s_k$ in $G$ there exists $yin C$ such that $G = langle s_i,yrangle$ for $
Ali Raza Rahimipour, Yousof Farzaneh
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Non-simple localizations of finite simple groups
Journal of Algebra, 2006 10 ...
Rodríguez, José L. +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source