Results 101 to 110 of about 1,101,064 (277)
Root systems and quotients of deformations of simple singularities [PDF]
Journal of Algebra, 2019 35 pages, 16 ...
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FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Geometric mean Newton’s method for simple and multiple roots
Applied Mathematics Letters, 2008 The classical Newton iteration formula to find a root of the equation \(f(x)= 0\) where \(f\) is a sufficiently differentiable real function is \(x_{n+1}= x_n- f(x_n)/f'(x_n)\). Because \[ f(x)= f(x_n)+ \int^x_{x_n} f'(y)\,dy, \] the Newton iteration formula can be interpreted as an approximation of the integral by \((x- x_n)\cdot f'(x_n)\).
Lukić, Tibor, Ralević, Nebojša M.
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Some Fixed Points Results of Quadratic Functions in Split Quaternions
Journal of Function Spaces, 2016 We attempt to find fixed points of a general quadratic polynomial in the algebra of split quaternion. In some cases, we characterize fixed points in terms of the coefficients of these polynomials and also give the cardinality of these points.
Young Chel Kwun +3 more
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Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Horticultural Plant JournalNon-heading Chinese cabbage, a variety of Brassica campestris, is an important vegetable crop in the Yangtze River Basin of China. However, the immaturity of its stable transformation system and its low transformation efficiency limit gene function ...
Huiyu Wang +5 more
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FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
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Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source