Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A Simple Panel-CADF Test for Unit Roots [PDF]
In this paper we propose a simple extension to the panel case of the covariate- augmented Dickey Fuller (CADF) test for unit roots developed in Hansen (1995).
Lupi, Claudio, Costantini, Mauro
core +2 more sources
Analysis of Traub’s Method for Cubic Polynomials
The dynamical analysis of Kurchatov’s scheme is extended to Traub’s method. The difference here is that Traub’s method requires two additional starting points. Therefore, the map is three-dimensional instead of 2-D.
Beny Neta
doaj +1 more source
Measurement of 33P-PO4 Absorption Capacity and Root-to-leaf Transfer in Arabidopsis
This method allows quantification of phosphate absorption capacity by Arabidopsis roots using very simple equipment, and can be scaled up or down.
Marie-Christine Thibaud, Elena Marin
doaj +1 more source
Ethylene supports colonization of plant roots by the mutualistic fungus Piriformospora indica [PDF]
The mutualistic basidiomycete Piriformospora indica colonizes roots of mono- and dicotyledonous plants, and thereby improves plant health and yield. Given the capability of P.
Jörg Durner +39 more
core +2 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
On the Number of Real Roots of a System of Trancendental Equations in a Given Domain
The paper is devoted to the study of the number of real roots of general systems of transcendental equations with real Taylor coefficients in some domain $D$ of multidimensional real space.
A.M. Kytmanov, O.V. Khodos
doaj +1 more source
A General Family of Fifth-Order Methods for Finding Simple Roots of Nonlinear Equations
In this paper, a new fifth-order family of methods free from second derivative is obtained. The new iterative family contains the King’s, which is one of the most well-known family of methods for solving nonlinear equations, and some other known methods ...
Behzad GHANBARI
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source

