Results 41 to 50 of about 103,109 (304)
The unit root property and optimality: a simple proof [PDF]
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openaire +2 more sources
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
A simple method suitable to study de novo root organogenesis
De novo root organogenesis is the process in which adventitious roots regenerate from detached or wounded plant tissues or organs. In tissue culture, appropriate types and concentrations of plant hormones in the medium are critical for inducing ...
Xiaodong eChen +5 more
doaj +1 more source
On Real Roots of Complement Degree Polynomial of Graphs.
Let G=(V,E) be a simple undirected graph of order xi n and let CD(G,i) be the set of vertices of degree i in complement graph and let Cdi(G)=|CD(G,i)|. Then complement degree polynomial of G is defined as CD[G,x]=$\sum_{i=\delta(\overline{G})}^{\Delta(
K Safeera, V Anil Kumar
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Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Projection of Polyhedra onto Coxeter Planes Described with Quaternions
3-dimensional convex uniform polyhedra have been projected onto their corresponding Coxeter planes defined by the simple roots of the Coxeter diagram ,
Mudhahir Al-Ajmi +2 more
doaj +1 more source
Polynomials, sign patterns and Descartes' rule of signs [PDF]
By Descartes' rule of signs, a real degree $d$ polynomial $P$ with all nonvanishing coefficients with $c$ sign changes and $p$ sign preservations in the sequence of its coefficients ($c+p=d$) has ${\rm pos}\leq c$ positive and $\neg\leq p$ negative roots,
Vladimir Petrov Kostov
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source

