Results 111 to 120 of about 5,215,765 (304)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Genome-wide characterization of simple sequence repeats in cucumber (Cucumis sativus L.)

BMC Genomics, 2010
Background Cucumber, Cucumis sativus L. is an important vegetable crop worldwide. Until very recently, cucumber genetic and genomic resources, especially molecular markers, have been very limited, impeding progress of cucumber breeding efforts ...
Simon Philipp W, Yang Luming, Senalik Douglas A, Cavagnaro Pablo F, Harkins Timothy T, Kodira Chinnappa D, Huang Sanwen, Weng Yiqun   +7 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Identification of simple sequence repeats: their distribution and primer design for chickpea genetics and breeding applications.

, 2014
Identification of simple sequence repeats: their distribution and primer design for chickpea genetics and breeding applications.
Rajeev K. Varshney (151116), Himabindu Kudapa (513727), Andrew D. Farmer (147049), Steven B. Cannon (245683), Bunyamin Taran (513729), Sarwar Azam (513728), Connor Cameron (513731), Rong Li (72042), Benjamin Deonovic (513730), Andrew G. Sharpe (492368)   +9 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Genome-wide identification of microsatellite markers from cultivated peanut (Arachis hypogaea L.)

BMC Genomics, 2019
Background Microsatellites, or simple sequence repeats (SSRs), represent important DNA variations that are widely distributed across the entire plant genome and can be used to develop SSR markers, which can then be used to conduct genetic analyses and ...
Qing Lu, Yanbin Hong, Shaoxiong Li, Hao Liu, Haifen Li, Jianan Zhang, Haofa Lan, Haiyan Liu, Xingyu Li, Shijie Wen, Guiyuan Zhou, Rajeev K. Varshney, Huifang Jiang, Xiaoping Chen, Xuanqiang Liang   +14 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Investigation of distal repetitive sequences in the genus allium [PDF]

, 2009
PhDThe telomere is a DNA/protein structure required to maintain the ends of linear chromosomes. Usually the DNA component comprises a highly conserved tandemly repeated minisatellite sequence.
Chester, Michael
core   +3 more sources

Scattergram of simple sequence repeats (SSRs) detected in the B. horsfieldi unigene sequences.

, 2018
Scattergram of simple sequence repeats (SSRs) detected in the B. horsfieldi unigene sequences.
Hua Yang (120668), Chunping Yang (691885), Jin Zhang (53297), Baoxin Wang (4504141), Wei Yang (109917), Fengrong Guan (4884697), Zhihang Zhuo (4884700), Yan Cai (298695), Yang Yang (45629)   +8 more
core   +1 more source