Results 91 to 100 of about 1,694,267 (336)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Media Practice in the Humanities Classroom [PDF]
, 2004 While there is good reason to be suspicious of the enthusiastic rush to integrate technology into the classroom, we in the humanities should embrace the opportunity it presents for media literacy and critical cultural ...
Walden, Elizabeth
core +1 more source
Judging a book by its cover: interface elements that affect reader selection of ebooks [PDF]
, 2012 Digital library research has demonstrated the impact of content presentation on both search and reading behaviours. In this paper, we scrutinise the influence of ebook presentation on user behaviour, focussing on document thumbnails and the first page ...
Buchanan, George +5 more
core +3 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Recent philosophy and the fiction/non-fiction distinction [PDF]
, 2018 Purpose - The purpose of this paper is to provide an overview of recent philosophical argument concerning the distinction between fiction and non-fiction. Design/methodology/approach - A critical view of the literature.
Matravers, Derek
core +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Research Note: Testing the Simple View of Reading in Adolescents and Adults With Down Syndrome. [PDF]
Am J Speech Lang Pathol, 2023 Loveall SJ, Conners FA, Hubbard KJ.
europepmc +1 more source
The simple view of reading in light of effects of vocabulary and working memory in Greek-Turkish bilingual children with and without dyslexia [PDF]
, 2023 Ifigeneia Dosi
openalex +1 more source
On (Not) Making Oneself Known [PDF]
, 2017 This chapter uses an exploration of the nature of selfhood in Hamlet to stage a discussion of the concept of literary knowledge. What does it mean to claim for our various practices of literary production that they can yield, collectively if not always ...
Gibson, John
core +1 more source