Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster+3 more
wiley +1 more source
Psycholinguistic screening test for Tamil children with reading difficulties in Sri Lanka
Reading development forms the cornerstone of every child’s educational journey, yet not all naturally acquire proficient reading skills, necessitating early identification and intervention.
Naina Mohamed Safeek
doaj
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf+10 more
wiley +1 more source
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
La mesure de l’analphabétisme en question. Le cas de l’Afrique subsaharienne
Sub-Saharan African countries are characterised by a high proportion of illiterate adults and this is not conducive to both economic growth and poverty reduction.
Alain Mingat+2 more
doaj +1 more source
The Contribution of Graphophonological-Semantic Flexibility to Reading Comprehension in College Students: Implications for a Less Simple View of Reading [PDF]
Kelly B. Cartwright
openalex +1 more source
Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang+6 more
wiley +1 more source
Alfonz Bednár: Sklený vrch, Glass Mount) [PDF]
The study about the Bednár´s debut Sklený vrch (The Glass Mount) is focused on an analysis of the stylistic, generic and generally aesthetic fragmentation and ambivalence in ideologically motivated prose work written actually in the post war period.
Zora Prušková
doaj
Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu+12 more
wiley +1 more source
Investigating English reading comprehension growth in adolescent language minority learners: some insights from the simple view [PDF]
Jeannette Mancilla‐Martinez+4 more
openalex +1 more source