Results 51 to 60 of about 123,484 (298)

Code and Comprehension in Written Language – Considering Limitations to the Simple View of Reading. [PDF]

open access: bronzeL1 Education Studies in Language and Literature, 2012
The Simple View of Reading (SVR) was introduced by Gough and Tunmer in 1986 as a model to predict reading comprehension by means of two factors: decoding and linguistic comprehension. Over time, the SVR has acquired the status of a definition of reading, and it counts as a starting point for both research and teaching programmes for reading.
Per Henning Uppstad   +1 more
openalex   +5 more sources

An experimental investigation into scope rigidity in written Mandarin

open access: yesFrontiers in Psychology, 2023
Mandarin Chinese is claimed to be a scope-rigid language, as its doubly-quantified simple transitive sentences are unambiguous with surface scope only and no inverse scope available.
Hongchen Wu
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

‘Everything is translatable, nothing is translatable’: the migrant as translated/translator in Nadeem Aslam’s Maps for Lost Lovers

open access: yesAngles, 2022
A translation is always a process and never a simple one or a complete one. The task of the translator is to transpose meanings allowing distant worlds to make sense of each other but this always bears with itself a dimension of failure as nothing can be
Daniela Vitolo
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Practical challenges in data‐driven interpolation: Dealing with noise, enforcing stability, and computing realizations

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Prediction of Reading Ability: A Cross-Validation Study of the Simple View of Reading [PDF]

open access: yesJournal of Literacy Research, 1997
The Simple View of Reading, as originally articulated by Gough and Tunmer (1986), proposes that reading comprehension ability can be predicted by the product term of two components: decoding and listening comprehension (R = D × L). Based on a longitudinal study evaluating developmental reading in bilingual children, Hoover and Gough (1990) reported ...
Frank R. Vellutino, Rusan Chen
openaire   +2 more sources

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

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