Results 51 to 60 of about 1,700,341 (334)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Truth or Meaning: Ricoeur versus Frei on Biblical Narrative [PDF]
, 1986 Of the theologians and philosophers now writing on biblical narrative, Hans Frei and Paul Ricoeur are probably the most prominent. It is significant that their views converge on important issues.
Comstock, Gary
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
An experimental investigation into scope rigidity in written Mandarin
Frontiers in Psychology, 2023 Mandarin Chinese is claimed to be a scope-rigid language, as its doubly-quantified simple transitive sentences are unambiguous with surface scope only and no inverse scope available.
Hongchen Wu
doaj +1 more source
First-Person Knowledge: Wittgenstein, Cavell, and "Therapy" [PDF]
, 2002 The recent publication of The New Wittgenstein signals the arrival of a distinctive "therapeutic" reading of Ludwig Wittgenstein"s philosophical enterprise. As announced in its Preface, this collection presents the "nonsense" of philosophy as the subject
Meyer, Thomas
core
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Angles, 2022 A translation is always a process and never a simple one or a complete one. The task of the translator is to transpose meanings allowing distant worlds to make sense of each other but this always bears with itself a dimension of failure as nothing can be
Daniela Vitolo
doaj +1 more source
Prediction of Reading Ability: A Cross-Validation Study of the Simple View of Reading [PDF]
Journal of Literacy Research, 1997 The Simple View of Reading, as originally articulated by Gough and Tunmer (1986), proposes that reading comprehension ability can be predicted by the product term of two components: decoding and listening comprehension (R = D × L). Based on a longitudinal study evaluating developmental reading in bilingual children, Hoover and Gough (1990) reported ...
Ru San Chen, Frank R. Vellutino
openaire +1 more source
The world’s negligence globalisation, philosophy and the misadventures of space [PDF]
, 2016 Las descripciones de nuestra época como un tiempo de desespacialización, desterritorialización y desmaterialización tecnológica merecen ser discutidos con el fin de evidenciar la compleja genealogía de los cambios a los que se refieren.
Marzocca, Ottavio
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source