Results 31 to 40 of about 129,464 (252)

Quando manca il detective. La presa in carico dell’investigazione in due racconti americani di fine Ottocento

open access: yesLinguae &: Rivista di Lingue e Culture Moderne, 2021
A Whisper in the Dark” by Louisa May Alcott (1877) and “The Yellow Wallpaper” by Charlotte Perkins Gilman (1892) offer an interesting, and not sufficiently investigated, perspective from the point of view of crime studies.
Alessandra Calanchi
doaj   +1 more source

Reading comprehension in a large cohort of French first graders from low socio-economic status families: a 7-month longitudinal study. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: The literature suggests that a complex relationship exists between the three main skills involved in reading comprehension (decoding, listening comprehension and vocabulary) and that this relationship depends on at least three other factors ...
Edouard Gentaz   +3 more
doaj   +1 more source

The Simple View of Reading as a cognitive framework for multilingual reading comprehension assessment

open access: yesFrontiers in Education
Reading is an essential skill that shapes success in both academic and everyday life. However, assessing how well students understand written materials remains a complex task, particularly in multilingual contexts, where different languages interact ...
Naila Fethi   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Critical Thinking in Reading Comprehension: Fine Tuning the Simple View of Reading

open access: yesEducation Sciences
Critical thinking has been identified as an essential skill for the 21st century, yet little research has investigated its role in reading comprehension.
David Paige   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Evaluating the Simple View of Reading Model: Longitudinal Testing and Applicability to the Swedish Language

open access: yesEducation Sciences
This study investigates the empirical validity of the simple view of reading model in a semi-transparent language, Swedish, by using a large amount of reading test data from 11,791 students. Data were collected during the primary grades (year 1–3), which
Thomas Nordström   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy