Results 61 to 70 of about 244,423 (295)

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

Advanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian, Guicheng Zhao, Xiang Wang, Xinyao Tang, Gan Shen, Tiechao Ruan, Chuan Jiang, Shikun Zhao, Jincheng Zhang, Xinyue Cui, Liangchai Zhuo, Jun Ma, Yihong Yang, Tingting Lin, Ying Shen   +14 more
wiley   +1 more source

Topology effect of two PSO and simplex hybrids

Revista Facultad de Ingeniería Universidad de Antioquia, 2010
En el presente artículo se muestran los resultados de optimización, utilizando un grupo de funciones estándar. Al hibridizar el algoritmo de optimización PSO (Particle Swarm Optimization) con el algoritmo simplex tradicional (SX, Nelder-Mead) de dos ...
Rodrigo Correa, Julio Carrillo, Oscar Reyes   +2 more
doaj  

Machine learning driven many‐objective moving horizon scheduling optimization

AIChE Journal, EarlyView.
Abstract Industrial electrification can decarbonize chemical manufacturing, but it exposes operations to volatile electricity prices and carbon intensities. This work develops a machine learning‐enhanced many‐objective moving horizon scheduling framework that predicts objective correlation groupings from 48‐hour price and emission‐intensity profiles ...
Hongxuan Wang, Andrew Allman
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Geometric shape parameterization of multidimensional finite non-regular point sets

Омский научный вестник
The paper is devoted to a formal approach to parameterization the geometric shape of spatial point irregular sets in multidimensional Euclidean space.
V. Yu. Yurkov, M. A. Chizhik
doaj   +1 more source

Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent [PDF]

, 2011
Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Mei-Ju Hsu, Frazer J. Rixon, Petermann, P., Rixon Frazer J., Rahn, E., Hsu Mei-Ju, Knebel-Mörsdorf, D., Geraghty, R.J., Dagmar Knebel-Mörsdorf, Rahn Elena, Philipp Petermann, Knebel-Mörsdorf Dagmar, Elena Rahn, Frazer J Rixon, Hsu, M.-J., Rixon, F.J., Petermann Philipp   +16 more
core   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

Particle Swarm Optimization as a Noise‐Tolerant Strategy for High‐Entropy Alloy Research

Advanced Intelligent Discovery, EarlyView.
A customized particle swarm optimization algorithm is benchmarked against batch Bayesian optimization across four high‐entropy alloy oxygen‐reduction landscapes. While both methods locate the global optimum comparably under noise‐free conditions, Bayesian optimization’s surrogate model tends to overfit noisy data.
Ahmad Tirmidzi, Matthias Arenz, Vladislav A. Mints   +2 more
wiley   +1 more source

Applications of the Hahn-Banach Theorem, a Solution of the Moment Problem and the Related Approximation

Mathematics
We start by an application the of Krein–Milman theorem to the integral representation of completely monotonic functions. Elements of convex optimization are also mentioned. The paper continues with applications of Hahn–Banach-type theorems and polynomial
Octav Olteanu
doaj   +1 more source

The john theorem for simplex

Journal of Shanghai University (English Edition), 2006
8 ...
Si, Lin, Xiong, Ge, Leng, Gangsong
openaire   +3 more sources