Results 51 to 60 of about 167,102 (266)

A case of hidroacanthoma simplex

open access: yesIndian Journal of Dermatology, 2013
We report a case of hidroacanthoma simplex with giant lesion that was found on the left lumbar part which was treated with surgical excision.
Xinfeng Lu   +5 more
openaire   +3 more sources

Lactate‐Driven Restriction of Mitochondrial Permeability Transition Promotes Resistance to Chemo‐Immunotherapy by Suppressing Tumor PANoptosis

open access: yesAdvanced Science, EarlyView.
Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong   +20 more
wiley   +1 more source

Topology effect of two PSO and simplex hybrids

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2010
En el presente artículo se muestran los resultados de optimización, utilizando un grupo de funciones estándar. Al hibridizar el algoritmo de optimización PSO (Particle Swarm Optimization) con el algoritmo simplex tradicional (SX, Nelder-Mead) de dos ...
Rodrigo Correa   +2 more
doaj  

Geometric shape parameterization of multidimensional finite non-regular point sets

open access: yesОмский научный вестник
The paper is devoted to a formal approach to parameterization the geometric shape of spatial point irregular sets in multidimensional Euclidean space.
V. Yu. Yurkov, M. A. Chizhik
doaj   +1 more source

The john theorem for simplex

open access: yesJournal of Shanghai University (English Edition), 2006
8 ...
Si, Lin, Xiong, Ge, Leng, Gangsong
openaire   +3 more sources

Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response

open access: yesAdvanced Science, EarlyView.
This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du   +10 more
wiley   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

open access: yes
Arthritis Care &Research, EarlyView.
Catherine Deffendall   +6 more
wiley   +1 more source

SDF‐1 Attenuates Oocyte Quality Decline During Reproductive Aging Through Autophagy‐Enhanced Stress Granule Scavenging

open access: yesAdvanced Science, EarlyView.
SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long   +12 more
wiley   +1 more source

Fibrillarin Resists Cellular Senescence Via SIRT1‐Dependent Nicotinamide Metabolism and Its Inhibition Sensitizes Senolytic Therapy in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
FBL directly binds to and stabilizes SIRT1 by blocking its ubiquitin‐proteasome degradation, thereby sustaining nicotinamide metabolism and redox homeostasis to counteract cellular senescence in ESCC. Genetic and pharmacological suppression of FBL sensitizes tumor cells to senolytic therapy.
Xing Jin   +9 more
wiley   +1 more source

Applications of the Hahn-Banach Theorem, a Solution of the Moment Problem and the Related Approximation

open access: yesMathematics
We start by an application the of Krein–Milman theorem to the integral representation of completely monotonic functions. Elements of convex optimization are also mentioned. The paper continues with applications of Hahn–Banach-type theorems and polynomial
Octav Olteanu
doaj   +1 more source

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