Results 101 to 110 of about 70,758 (262)

The opportunities and challenges of epigenetic approaches to manage herpes simplex infections

Expert Review of Anti-infective Therapy
Despite the existence of antivirals that potently and efficiently inhibit the replication of herpes simplex virus 1 and 2 (HSV-1, -2), their ability to establish and maintain, and reactivate from, latency has precluded the development of curative therapies. Several groups are exploring the opportunities of targeting epigenetic regulation to permanently
Saddoris, Sarah M, Schang, Luis M
openaire   +2 more sources

Analysis of individualized brain–gut association networks and transcriptional patterns in major depressive disorder

Interdisciplinary Medicine, EarlyView.
Individualized brain–gut association networks suggest potential neuropathological mechanisms in MDD and MDDSI. Multilevel brain–gut association changes involving HSV‐1 and inflammation may be relevant to MDD, whereas alterations related to insulin metabolism may play a potential role in the neuropathological mechanisms of MDDSI.
Wei Wang, Baoyuan Zhu, Yuanyuan Huang, Liqin Liang, Zhaobo Li, Yunheng Diao, Minxin Guo, Heng Zhang, Jing Zhou, Fengchun Wu, Kai Wu   +10 more
wiley   +1 more source

Methods of Multi-Criteria Optimization of Technological Processes in a Fuzzy Environment Based on the Simplex Method and the Theory of Fuzzy Sets

Mathematics
Many modern technological objects in practice are characterized by the uncertainty of the initial information necessary for their management. Recently, one of the pressing scientific and practical problems is the development of new optimization methods ...
Batyr Orazbayev, Kulman Orazbayeva, Yerbol Ospanov, Salamat Suleimenova, Lyailya Kurmangaziyeva, Valentina Makhatova, Yerlan Izbassarov, Aigerim Otebaeva   +7 more
doaj   +1 more source

Body weight in autism spectrum disorder: A systematic review and meta‐analysis

JCPP Advances, EarlyView.
Abstract Background Evidence on the relationship of autism spectrum disorder (ASD) to overweight/obesity and underweight is mixed. Moreover, it is unclear how this relationship changes with age. Methods We carried out a systematic review (SR) with meta‐analysis on the association between ASD and obesity, overweight and underweight across the life span.
Victoria Nieuwenhuys‐Ruiz, Leyre Gambra, Samuele Cortese, Pablo Lizoain, Diana Rodriguez‐Romero, Ursula Paiva, Carmen Gándara, Sara Magallón, Gonzalo Arrondo   +8 more
wiley   +1 more source

Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes

Journal of Intelligent Medicine, EarlyView.
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang, Zhentao Zhou, Lirong Zhu, Wei Liu   +3 more
wiley   +1 more source

Microbial communities and functional diversity in seafood

JSFA reports, EarlyView.
Abstract Functional diversity encompasses ecosystem processes that enhance adaptability to environmental change. This study explores the diversity of microorganisms associated with seafood. In this paper, we present our knowledge of microbial diversity in relation to seafood.
Christian Larbi Ayisi, Samuel Ayeh Osei, Grace Afumwaa Boamah, Gertrude Dzifa Mensah   +3 more
wiley   +1 more source

HPV‐6 Positive Eruptive Verruca Vulgaris After Upadacitinib Initiation for Severe Atopic Dermatitis

JEADV Clinical Practice, EarlyView.
ABSTRACT Oral JAK‐1 inhibitors for atopic dermatitis (AD) are associated with an increased risk of cutaneous viral infections, particularly herpes zoster. Emerging case reports further suggest a link to eruptive human papillomavirus (HPV) disease. A 23‐year‐old transgender man (female‐to‐male) with severe AD developed a rapidly disseminating eruption ...
Mohammed Shanshal, Emily Moon, Georgios Kallikas   +2 more
wiley   +1 more source

Mapping landowners' willingness to allow recreational deer harvest on their property for managing chronic wasting disease

The Journal of Wildlife Management, EarlyView.
We demonstrate an approach for mapping the probability of landowners' willingness to allow wildlife management actions on their property using chronic wasting disease as a case study. Larger property sizes were associated with higher landowner willingness. We mapped predictions across the contiguous United States at the census tract level.
Eric C. Palm, Matthew A. Williamson, Nathan P. Snow, Sonja Christensen   +3 more
wiley   +1 more source

Cold Gas Sprayed Titanium Coating for Corrosion Protection of Bipolar Plates in Proton Exchange Membrane Water Electrolysis

Materials and Corrosion, EarlyView.
Climate‐neutral green hydrogen is produced via water electrolysis using renewable energy. This study explores using cold gas spraying to apply titanium coatings on steel bipolar plates for proton exchange membrane water electrolyzers. The coating shows effective corrosion protection, presenting a promising solution for future designs.
Kirsten Bobzin, Marvin Erck, Kevin Jasutyn, Katja Radermacher   +3 more
wiley   +1 more source

Hearing the Serre Invariant of a Compact p‐Adic Analytic Manifold

Mathematische Nachrichten, EarlyView.
ABSTRACT Using a previous novel way of defining kernel functions for Laplacian integral operators on a compact p$p$‐adic analytic manifold X$X$, one such operator Δ0s$\Delta _0^s$ with s∈R$s\in \mathbb {R}$ is applied to hearing the Serre invariant i(X)$i(X)$ by showing that a wavelet eigenvalue (with the wavelet having small support) is always ...
Patrick Erik Bradley, Ángel Morán Ledezma   +1 more
wiley   +1 more source