Results 111 to 120 of about 10,934,980 (285)

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti‐tumor necrosis factor alpha therapy in children

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in pediatric inflammatory bowel disease (PIBD) with biologics, remission rates remain at 47%–60% with loss‐of‐response rates at 60%–68%. Evidence for efficacy of dual biologic therapy (DBT) with anti‐tumor necrosis factor alpha therapy (anti‐TNF‐α)‐ vedolizumab (VDZ) for children refractory to anti‐TNF‐α therapy is ...
Jonathan E. M. O'Donnell, Carlie Bolles, Claire R. Reilly, Manal Morgan, Christopher Burgess, Fariha Balouch, Peter J. Lewindon   +6 more
wiley   +1 more source

A Multi-Layer Resilient Architecture for Autonomous Quadcopter-Based Bridge Inspection Under Environmental Uncertainties

Drones
This paper presents a multi-layer architecture designed to enhance the reliable autonomous flight of single and multiple quadcopters in simulation. The architecture leverages concepts inspired by the resilient spacecraft executive to hierarchically ...
Zhenyu Shi, Donghoon Kim
doaj   +1 more source

Microbial communities and functional diversity in seafood

JSFA reports, EarlyView.
Abstract Functional diversity encompasses ecosystem processes that enhance adaptability to environmental change. This study explores the diversity of microorganisms associated with seafood. In this paper, we present our knowledge of microbial diversity in relation to seafood.
Christian Larbi Ayisi, Samuel Ayeh Osei, Grace Afumwaa Boamah, Gertrude Dzifa Mensah   +3 more
wiley   +1 more source

Early and Accurate Pathogen Identification Based on mNGS: Key to Timely Therapy for Mycoplasma Prosthetic Joint Infection

Orthopaedic Surgery
Objectives Prosthetic joint infection (PJI) caused by Mycoplasma infection is relatively rare in clinical practice; all cases are primarily reported as individual case reports, and the characteristics of PJI induced by Mycoplasma infection have not been ...
Zhenyuan Lin, Yang Chen, Zhenggui Yu, Zeyu Zhang, Yiming Lin, Wenming Zhang, Wenbo Li, Yufeng Guo, Xinyu Fang   +8 more
doaj   +1 more source

Th2/Th17 Inflammation: Pathogenic Drivers and Therapeutic Targets in Darier and Hailey‐Hailey Diseases

JEADV Clinical Practice, EarlyView.
Skin samples of Hailey‐Hailey and Darier diseases were analyzed for inflammatory and barrier markers using indirect immunofluorescence and transcriptomic techniques. A mixed Th2/Th17 inflammatory pattern and altered expression of barrier markers were observed.
Ella Glodjajic, Darko Stojkov, Joanna Boros‐Majewska, Jeremy Di Domizio, Michel Gilliet, Christoph Schlapbach, Timothée Fettrelet, Luca Borradori, Hans‐Uwe Simon, Dagmar Simon, Susanne Radonjic‐Hoesli   +10 more
wiley   +1 more source

Application and tolerability of Herpotherm® in the treatment of genital herpes

Clinical, Cosmetic and Investigational Dermatology, 2013
Gerrit Schlippe,1 Werner Voss,1 Lars Christian Brenn2 1Dermatest Medical Research Company, Münster, Germany; 2RIEMSER Pharma GmbH, Greifswald, Germany Abstract: Genital herpes is the manifestation of a herpes simplex virus 2 infection.
Schlippe G, Voss W, Brenn LC
doaj  

Herpes simplex - a new approach

, 1983
Herpes simplex is a viral disease caused by herpes simplex viruses that are characterized by their ability to take permanent residence in the host causing infections. Acyclovir is the first selective medication that is used particularly against herpes viruses by means of a two stage mechanism, namely, by a selective concentration in infected cells and ...
openaire   +1 more source

Cold Gas Sprayed Titanium Coating for Corrosion Protection of Bipolar Plates in Proton Exchange Membrane Water Electrolysis

Materials and Corrosion, EarlyView.
Climate‐neutral green hydrogen is produced via water electrolysis using renewable energy. This study explores using cold gas spraying to apply titanium coatings on steel bipolar plates for proton exchange membrane water electrolyzers. The coating shows effective corrosion protection, presenting a promising solution for future designs.
Kirsten Bobzin, Marvin Erck, Kevin Jasutyn, Katja Radermacher   +3 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

The opportunities and challenges of epigenetic approaches to manage herpes simplex infections

Expert Review of Anti-infective Therapy
Despite the existence of antivirals that potently and efficiently inhibit the replication of herpes simplex virus 1 and 2 (HSV-1, -2), their ability to establish and maintain, and reactivate from, latency has precluded the development of curative therapies. Several groups are exploring the opportunities of targeting epigenetic regulation to permanently
Saddoris, Sarah M, Schang, Luis M
openaire   +2 more sources