Results 31 to 40 of about 70,758 (262)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

On the Simplex-based methods for Neutrosophic linear programming problems [PDF]

Journal of Fuzzy Extension and Applications
This paper investigates Neutrosophic Linear Programming (NLP) and focuses on one of the most suitable approaches to solve it, which is called the Simplex-based model.
Sulima Ahmed Mohammed Zubair, Najla ELzein AbuKaswi Osman, Wiem Abedelmonem Salah Ben Khalifa, Amal Hassan Mohammed Yassin   +3 more
doaj   +1 more source

Cross-species utility of microsatellite loci for the genetic characterisation of Anisakis berlandi (Nematoda: Anisakidae)

Parasite, 2020
Eight microsatellite loci, recently developed in the species Anisakis pegreffii, were successfully amplified in Anisakis berlandi, sibling species of the A. simplex (s. l.) complex. They were validated on adult specimens (n = 46) of the parasite species,
Bello Eleonora, Paoletti Michela, Webb Stephen C., Nascetti Giuseppe, Mattiucci Simonetta   +4 more
doaj   +1 more source

SIMPLEX: Multiple phase-cycled bSSFP quantitative magnetization transfer imaging with physic-guided simulation learning of neural network

NeuroImage, 2023
Most quantitative magnetization transfer (qMT) imaging methods require acquiring additional quantitative maps (such as T1) for data fitting. A method based on multiple phase-cycled bSSFP was recently proposed to enable high-resolution 3D qMT imaging ...
Huan Minh Luu, Sung-Hong Park
doaj   +1 more source

The Case of a 40‐Year‐Old Man With New‐Onset Status Epilepticus in the Setting of HIV Infection

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 40‐year‐old man from Andhra Pradesh in India, while on regular antiretroviral treatment (ART) for long‐standing HIV infection presented with a 1‐day history of new‐onset status epilepticus. CT and MRI brain showed multifocal cerebral ring lesions, some of which demonstrated characteristic ‘hole‐with‐a‐dot’ sign.
Vadde Akhil, Ramachandiran Nandhagopal
wiley   +1 more source

Ciri dan Pola Kalimat Simpleks Bahasa Yewena di Distrik Depapre Kabupaten Jayapura Papua

Ranah: Jurnal Kajian Bahasa, 2023
Yewena is one of the languages spoken in four villages namely Yepase, Wambena, Doromena, and Yewena in Depapre District. The purpose of this study is to describe the characteristics and syntactic patterns of simplex sentences in Yewena language.
Grace J.M. Mantiri, Henry Ch. Iwong
doaj   +1 more source

Supramolecular Polymer‐Surfactant Co‐Assemblies for Multivalent HSV‐1 Inhibition

Angewandte Chemie, EarlyView.
Non‐covalent co‐assembly of BTA with antiviral surfactants produces ratio‐dependent morphologies. Fibrous supramolecular polymers exhibit superior HSV‐1 inhibition, revealing multivalent fiber‐virus interactions and highlighting supramolecular co‐assemblies as a powerful strategy for functional biomedical nanomaterials with demonstrated tunable ...
Christian Zoister, Boris Schade, Paulina Sittinger, Xianwen Lou, Esmee de Korver, Freek V. de Graaf, Ranen Etouki, Chuanxiong Nie, Kai Licha, Kai Ludwig, Abhishek Kumar Singh, E. W. Meijer, Rainer Haag   +12 more
wiley   +2 more sources

Portable Molecularly Imprinted Polymer Sensor for Rapid Swab‐Based Detection of Norovirus

Advanced Healthcare Materials, EarlyView.
This work reports a rapid, portable smartphone‐based sensor capable of detecting four norovirus genotypes from swab samples within 15 min. Sensor selectivity was validated through evaluation against four common live viruses. The swab‐based sampling process enabled simple sample preparation combined with the compact detection system, supporting use of ...
Amy Dann, Pankaj Singla, Minji Kim, Sloane Stoufer, Clare Thomas, Robert D. Crapnell, Craig E. Banks, Jake McClements, Shayan Seyedin, Mark Geoghegan, Samuel T. Jones, Christopher F. Blanford, Matthew D. Moore, Marloes Peeters   +13 more
wiley   +1 more source

The calcitonin receptor gene is a candidate for regulation of susceptibility to herpes simplex type 1 neuronal infection leading to encephalitis in rat. [PDF]

PLoS Pathogens, 2012
Herpes simplex encephalitis (HSE) is a fatal infection of the central nervous system (CNS) predominantly caused by Herpes simplex virus type 1. Factors regulating the susceptibility to HSE are still largely unknown.
Nada Abdelmagid, Biborka Bereczky-Veress, André Ortlieb Guerreiro-Cacais, Petra Bergman, Katarina M Luhr, Tomas Bergström, Birgit Sköldenberg, Fredrik Piehl, Tomas Olsson, Margarita Diez   +9 more
doaj   +1 more source