Results 51 to 60 of about 70,758 (262)

ANALISIS PERBANDINGAN METODE FUZZY SIMPLEKS DAN KUMAR DALAM OPTIMASI PRODUKSI FULLY FUZZY LINEAR PROGRAMMING

E-Jurnal Matematika
This study discusses a comparative analysis between the fuzzy simplex method and Kumar’s method in solving production optimization problems based on Fully Fuzzy Linear Programming (FFLP).
NERLI KHAIRANI, RIZAL MUHAIMIN, NAFASA ZAHRI, NAYSLA AURA SIFFA   +3 more
doaj   +1 more source

SDF‐1 Attenuates Oocyte Quality Decline During Reproductive Aging Through Autophagy‐Enhanced Stress Granule Scavenging

Advanced Science, EarlyView.
SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long, Meng Wang, Ruolin Mao, Hong Chen, Juepu Zhou, Xiangfei Wang, Zheng Yuan, Ri‐Cheng Chian, Nan Xiao, Qingsong Xi, Yimin Shu, Lei Jin, Lixia Zhu   +12 more
wiley   +1 more source

A mucosal vaccination approach for herpes simplex virus type 2 [PDF]

Vaccine, 2011
An estimated 1 out of every 5 Americans is infected with herpes simplex virus type 2 (HSV-2). Efforts in developing a potent vaccine for HSV-2 have shown limited success. Here we describe a heterologous vaccination strategy for HSV-2 based on an intramuscular DNA prime followed by a liposome-encapsulated antigen boost delivered intranasally.
Rebecca S, Tirabassi, Christopher I, Ace, Tatyana, Levchenko, Vladimir P, Torchilin, Liisa K, Selin, Siwei, Nie, Dennis L, Guberski, Kejian, Yang   +7 more
openaire   +2 more sources

Fibrillarin Resists Cellular Senescence Via SIRT1‐Dependent Nicotinamide Metabolism and Its Inhibition Sensitizes Senolytic Therapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
FBL directly binds to and stabilizes SIRT1 by blocking its ubiquitin‐proteasome degradation, thereby sustaining nicotinamide metabolism and redox homeostasis to counteract cellular senescence in ESCC. Genetic and pharmacological suppression of FBL sensitizes tumor cells to senolytic therapy.
Xing Jin, Hong Liu, Ling Gao, Lei Liu, Ji‐Bin Liu, Xiaoxia Jin, Ming‐Song Wang, Dan Liu, Li Feng, Wen‐Lian Chen   +9 more
wiley   +1 more source

Herpes simplex virus: isolation, cytopathological characterization and antiviral sensitivity [PDF]

Anais Brasileiros de Dermatologia, 2014
BACKGROUND:Herpes simplex virus (HSV) infection is an endemic disease and it is estimated that 6095% of the adult population are infected with symptoms that are usually self-limiting, though they can be serious, extensive and prolonged in ...
Carlos Nozawa, Lilian Yumi Hattori, Ligia Carla Faccin Galhardi, Nayara Lopes, Wesley Andrade Bomfim, Ligyana Korki de Cândido, Elbens Marcos Minoreli de Azevedo, Airton dos Santos Gon, Rosa Elisa Carvalho Linhares   +8 more
doaj   +1 more source

Interpretability and Representability of Commutative Algebra, Algebraic Topology, and Topological Spectral Theory for Real‐World Data

Advanced Intelligent Discovery, EarlyView.
This article investigates how persistent homology, persistent Laplacians, and persistent commutative algebra reveal complementary geometric, topological, and algebraic invariants or signatures of real‐world data. By analyzing shapes, synthetic complexes, fullerenes, and biomolecules, the article shows how these mathematical frameworks enhance ...
Yiming Ren, Guo‐Wei Wei
wiley   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Geometric shape parameterization of multidimensional finite non-regular point sets

Омский научный вестник
The paper is devoted to a formal approach to parameterization the geometric shape of spatial point irregular sets in multidimensional Euclidean space.
V. Yu. Yurkov, M. A. Chizhik
doaj   +1 more source