Results 41 to 50 of about 70,758 (262)
The Journal of Physical Chemistry A, 2005 GTI-simplex is a new methodology that combines the generalized topological indices and the down hill simplex optimization procedure to search for optimized quantitative structure-property relationship models (Chem. Phys. Lett. 2005, 410, 343). In this study, the fundamental role of the graph topological distance inducing a local shell structure on ...
Matamala, AR, Estrada, E
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Stability of Medicinal Nanoemulsions to Spaceflight: Insights From the StarMed Experiment
Advanced Healthcare Materials, EarlyView.Chitosan‐coated melatonin nanoemulsions (MN) recovered from a sounding rocket mission preserve droplet size and controlled‐release behavior, whereas uncoated nanoemulsions show ageing‐driven droplet growth and increased accessible drug fraction. Simple polymer coatings thus enhance the flight resilience of liquid space medicines under cumulative launch
Modupe Adebowale +4 more
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Consensus Formation and Change are Enhanced by Neutrality
Advanced Science, EarlyView.Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag +3 more
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Journal of Numerical Analysis and Approximation Theory, 2017 In this paper, we deal with a numerical comparison between two exact simplicial methods for solving a capacitated four-index transportation problem. The first method was developed by R. Zitouni and A.
Rachid Zitouni, Mohamed Achache
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On Minimal Absorption Index for an n-Dimensional Simplex
Моделирование и анализ информационных систем, 2018 Let \(n\in{\mathbb N}\) and let \(Q_n\) be the unit cube \([0,1]^n\). For a nondegenerate simplex \(S\subset{\mathbb R}^n\), by \(\sigma S\) denote the homothetic copy of \(S\) with center of homothety in the center of gravity of \(S\) and ratio of ...
Mikhail V. Nevskii, Alexey Y. Ukhalov
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Advanced Science, EarlyView.RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu +13 more
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Simplex: Single Molecule Approach to Protein Complexes [PDF]
Biophysical Journal, 2011 Single molecule approaches were applied to limited systems due to several technical challenges. We report novel technical advance of studying proteins that are directly extracted from human cells. We found that tandem purification (see figure) is sufficient for observing single molecule events without any false positives.
Yeom, Kyu-Hyeon +4 more
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Topology‐Aware Deep Learning on Higher‐Order Structures for Drug Response Prediction
Advanced Science, EarlyView.We present TopDr, a topology‐aware deep learning framework that encodes both drugs and cell lines as multiscale simplicial complexes, capturing interactions at the 0‐, 1‐, and 2‐simplex levels. By jointly integrating local higher‐order neighborhoods and global topological structures, TopDr generates enriched representations for sensitivity prediction ...
Cong Shen +3 more
wiley +1 more source
Scientific Reports, 2021 The endoscopic features between herpes simplex virus (HSV) and cytomegalovirus (CMV) esophagitis overlap significantly, and hence the differential diagnosis between HSV and CMV esophagitis is sometimes difficult.
Jung Su Lee +9 more
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Exact Discrete Stochastic Simulation With Deep‐Learning‐Scale Gradient Optimization
Advanced Science, EarlyView.A 203,796‐parameter gene regulatory network classifies handwritten digits with 98.4% accuracy using exact stochastic dynamics. The framework decouples forward simulation from backward differentiation, making continuous‐time Markov chain models compatible with deep‐learning optimization.
Jose M. G. Vilar, Leonor Saiz
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