Results 31 to 40 of about 11,152,389 (276)

Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response

Advanced Science, EarlyView.
This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du, Liping Wang, Sujing Diao, Juan Li, Lei Zhao, Yan Yan, Haimin Li, Weiren Dong, Wei Wu, Jinyan Gu, Jiyong Zhou   +10 more
wiley   +1 more source

Comparison of the Method of Least Squares and the Simplex Method for Processing Geodetic Survey Results / Porovnanie Metódy Najmenších Štvorcov A Simplexovej Metódy Pri Spracovaní Výsledkov Geodetických Meran

GeoScience Engineering, 2013
Predložený príspevok je venovaný použitiu simplexovej metódy pri spracovaní výsledkov geodetických meraní v porovnaní so štandardne používanou metódou najmenších štvorcov (MNŠ).
Gašincová Silvia, Gašinec Juraj
doaj   +1 more source

Penyelesaian Metode Quick Simplex Terhadap Metode Dua Fase dengan Dua Elemen secara Simultan pada Kasus Minimum

Kubik, 2021
Linear programming is a way to solve the problemof allocating limiter resources optimally. One of the methods used in solving the simplex method for mixed constraints is the two-phase method.
Elfira Safitri, Sri Basriati, Mohammad Soleh, Ade Novia Rahma   +3 more
doaj   +1 more source

SDF‐1 Attenuates Oocyte Quality Decline During Reproductive Aging Through Autophagy‐Enhanced Stress Granule Scavenging

Advanced Science, EarlyView.
SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long, Meng Wang, Ruolin Mao, Hong Chen, Juepu Zhou, Xiangfei Wang, Zheng Yuan, Ri‐Cheng Chian, Nan Xiao, Qingsong Xi, Yimin Shu, Lei Jin, Lixia Zhu   +12 more
wiley   +1 more source

ALGORITHMS FOR CONSTRUCTING A REGRESSION LINEAR WITH RESPECT TO UNKNOWN COEFFICIENTS ON A LIMITED AMOUNT OF EXPERIMENTAL DATA

Вісник Національного технічного університету "ХПÌ": Системний аналіз, управління та інформаційні технології
This publication continues the series of scientific works of the authors on the creation of algorithms for constructing multivariate regressions which are linear with respect to unknown coefficients by using linear programming models.
Alexander Pavlov, Anton Kushch
doaj   +1 more source

A Safety Warning Model Based on IAHA-SVM for Coal Mine Environment

Sensors, 2023
Coal is an important resource that is closely related to people’s lives and plays an irreplaceable role. However, coal mine safety accidents occur from time to time in the process of working underground.
Zhen Li, Feng Feng
doaj   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

The s-monotone index selection rules for pivot algorithms of linear programming [PDF]

, 2012
In this paper we introduce the concept of s-monotone index selection rule for linear programming problems. We show that several known anti-cycling pivot rules like the minimal index, Last-In–First-Out and the most-often-selected-variable pivot rules are ...
Nagy, Adrienn, Illés, Tibor, Csizmadia, Zsolt   +2 more
core   +5 more sources