Results 81 to 90 of about 190,413 (302)
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Some Cautions Regarding Tax Simplification
Although tax simplification enjoys the attractiveness of being the opposite of complexity, it can have untoward effects as illustrated by the examples of a capitation tax, an international income tax regime that lacks rigorous base protection measures ...
Fleming, J. Clifton, Jr.
core
PLAIN-LANGUAGE APPROACH IN LEGISLATIVE DRAFTING: A PERSPECTIVE FROM POLAND
The purpose of this research is to explore plain-language postulates reflecting on legal drafting assumptions since legal acts should be precise, clear and express with no doubts the intention of the legislator.
Natalia ZYCH
doaj +2 more sources
Since the introduction of the translation universal hypothesis, validation efforts have predominantly focused on English and other European languages. However, studies on translated Chinese, particularly those involving language pairs beyond English and
Guo Zhen
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Adhesive dentistry has undergone a significant evolution, transitioning from classical multi-step adhesives to simplified single-bottle or universal adhesives and now towards self-adhesive composites that no longer require a separate adhesive.
Andreas Rathke +2 more
doaj +1 more source
The Sisyphus paradox of cutting red tape and managing public risk<br> The Dutch case
Cutting red tape has been topical in Dutch debates on legislative politics ever since the beginning of the 1990s, but has gained impetus – since 2003 – in the political arena as the combined consequence of the regulatory reform policies of the Balkenende
Wim J.M. Voermans
doaj +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
On Operations in Automatic Text Simplification
This paper explores the literature of automatic text simplification (ATS) centered on the notion of operations. Operations are the processes of applying certain modifications to a given text in order to transform it.
Cardon, Rémi +2 more
core

