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Plant responses to real and simulated microgravity
Life Sciences in Space Research, 2021Plant biology experiments in real and simulated microgravity have significantly contributed to our understanding of physiology and behavior of plants. How do plants perceive microgravity? How that perception translates into stimulus? And in turn plant's response and adaptation to microgravity through physiological, cellular, and molecular changes have ...
Malarvizhi, Sathasivam +3 more
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Secondary metabolism in simulated microgravity
The Chemical Record, 2001AbstractWe have studied microbial secondary metabolism in a simulated microgravity (SMG) environment provided by NASA rotatingâwall bioreactors (RWBs). These reactors were designed to simulate some aspects of actual microgravity that occur in space. Growth and product formation were observed in SMG in all cases studied, i.e., Bacillus brevis produced ...
A L, Demain, A, Fang
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Neurophysiological adaptations to spaceflight and simulated microgravity
Clinical Neurophysiology, 2021Changes in physiological functions after spaceflight and simulated spaceflight involve several mechanisms. Microgravity is one of them and it can be partially reproduced with models, such as head down bed rest (HDBR). Yet, only a few studies have investigated in detail the complexity of neurophysiological systems and their integration to maintain ...
Buoite Stella A. +3 more
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Simulation of blood flow in microgravity
The American Journal of Surgery, 1992Knowledge of venous, capillary, and arterial blood flow in microgravity is required to modify hemostatic techniques for control of bleeding in traumatic injuries or surgical procedures in space. To simulate human arterial, venous, and capillary bleeding, fresh whole bovine blood was injected by two operators at calculated flow rates (3.5, 7, and 14 mL ...
K, McCuaig +3 more
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Simulated microgravity (SMG) and bacteria.
Rivista di biologia, 2003This past century has been a scientific revolution in the understanding of the cell as the basic unit of life. However an immense paucity of knowledge exists on microbial growth, survival, function and structure in space. However, there are significant constraints placed on conducting biological research in space such as time, available stowage space ...
Huitema, Carly +2 more
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Validity of microgravity simulation models on Earth
American Journal of Kidney Diseases, 2001Many studies have used water immersion and head-down bed rest as experimental models to simulate responses to microgravity. However, some data collected during space missions are at variance or in contrast with observations collected from experimental models. These discrepancies could reflect incomplete knowledge of the characteristics inherent to each
Regnard, J +3 more
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Secondary Metabolism in Simulated Microgravity and Space Flight [PDF]
Protein and Cell, 2011 Space flight experiments have suggested that microgravity can affect cellular processes in microorganisms. To simulate the microgravity environment on earth, several models have been developed and applied to examine the effect of microgravity on secondary metabolism.
Lixin Zhang, Hong Gao, Zhiheng Liu
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The effect of simulated microgravity on hybridoma cells
Acta Astronautica, 2005The effect of clinostat-simulated microgravity on SP-2/0 and 1D6 hybridoma cells was studied. Clinorotation during 4-5 days at 1.5 rounds per minute decreased dramatically their proliferating capacity: the rotated cells divided less than once while control cells performed 4-5 divisions. They decreased the non-specific adhesion to tissue culture plastic,
Marina V, Skok +7 more
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Effect of simulated microgravity on vascular contractility
Journal of Applied Physiology, 1998Microgravity was simulated in Sprague-Dawley (SD) and Wistar (W) rats by using a tail harness to elevate the hindquarters, producing hindlimb unweighting (HU). After 20 days of HU treatment, blood vessels from both HU and control rats were cut into 3-mm rings and mounted in tissue baths for the measurement of isometric contraction.
R E, Purdy +4 more
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Body fluid metabolism at actual and simulated microgravity
Medicine & Science in Sports & Exercise, 1996Recent observations from space missions indicate that weightlessness does not induce an increase in diuresis and natriuresis in astronauts. Rather, both oral fluid and sodium intake as well as renal fluid and sodium output appear reduced compared with the preflight condition.
Gerzer, R., Heer, M., Drummer, C.
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