Results 151 to 160 of about 4,453 (185)

Simulated microgravity accelerates aging in Saccharomyces cerevisiae

Life Sciences in Space Research, 2021
The human body experiences physiological changes under microgravity environment that phenocopy aging on Earth. These changes include early onset osteoporosis, skeletal muscle atrophy, cardiac dysfunction, and immunosenescence, and such adaptations to the space environment may pose some risk to crewed missions to Mars.
Ana Paula Montanari, Fukuda, Vittoria de Lima, Camandona, Kelliton José Mendonça, Francisco, Rafaela Maria, Rios-Anjos, Claudimir, Lucio do Lago, Jose Ribamar, Ferreira-Junior   +5 more
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Interactions of Microcarriers in Simulated Microgravity

Advances in Heat and Mass Transfer in Biotechnology, 1999
Abstract In this study, we developed a numerical model that simulated the simultaneous motion of several microcarriers in the simulated microgravity environment of the NASA HARV bioreactor. Simulations were used to predict the interaction and collision of these multiple particles under different initial seeding densities.
David F. Meaney, Eric D. Johnston, Mitchell Litt, Solomon R. Pollack   +3 more
openaire   +1 more source

[Change of pulmonary circulation in microgravity and simulated microgravity].

Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering, 2002
Fluid is transferred cephalad in microgravity and simulated microgravity, and the pulmonary circulation is the first to be affected. Blood and fluid contents in the lungs increase, but unevenly distributed among various zones of the lungs. Blood vessels in the lungs are filled and distend.
L, Sun, Q L, Xiang, D S, Wang, W, Ren
openaire   +1 more source

Energy, protein, and substrate metabolism in simulated microgravity

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1995
Whole body protein turnover and energy expenditure before and during an oral glucose tolerance test (1 g/kg body wt) were studied on separate occasions in six healthy young men before and during 3 days of simulated microgravity using the 6 degrees head-down tilt (HDT) method.
K J, Acheson, J, Décombaz, C, Piguet-Welsch, F, Montigon, B, Decarli, I, Bartholdi, E B, Fern   +6 more
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GASTROINTESTINAL FUNCTION IN SIMULATED SPACE FLIGHT MICROGRAVITY

Digestive and Liver Disease, 2009
S140 P. Iovino 1, G. Bilancio 2, R. Tortora1, C. Bucci 1, A. Pascariello 1 , M. Siniscalchi 1 , C. Ciacci ∗ ,1 1Università Federico II, Napoli; 2Nefrologia Seconda Università, Napoli Background and aim: Head-down bed rest condition (HDBR) is a microgravity model simulating condition of space flight.
IOVINO, Paola, BILANCIO, GIANCARLO, Tortora R, BUCCI, CRISTINA, Pascariello A, Siniscalchi M, CIACCI, Carolina   +6 more
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Simulated microgravity upregulates an endothelial vasoconstrictor prostaglandin

Journal of Applied Physiology, 2001
Endothelial nitric oxide contributes to the vascular hyporesponsiveness to norepinephrine (NE) observed in carotid arteries from rats exposed to simulated microgravity. The goal of the present study was to determine whether a cyclooxygenase product of arachidonic acid also influences vascular responsiveness in this setting.
D S, Sangha, S, Han, R E, Purdy
openaire   +2 more sources

From hypergravity to microgravity: Choosing the suitable simulator

Microgravity - Science and Technology, 2006
Cardiovascular system functions are impaired in altered gravity conditions. In particular endothelial cells play a major role being responsible for the integrity of the vascular wall. Due to obvious difficulties in performing continuous and exhaustive experiments in space, most of the available data have been obtained so far using various simulators of
Bradamante S, Barenghi L, Versari S, Villa A   +3 more
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Hemodynamic effects of microgravity and their ground-based simulations

Acta Astronautica, 1991
Hemodynamic effects of simulated microgravity were investigated, in various experiments, using radioactive isotopes, in which 40 healthy men, aged 35 to 42 years, took part. Blood shifts were evaluated qualitatively and quantitatively. Simulation studies included bedrest, head-down tilt (-5 degrees and -15 degrees), and vertical water immersion, it ...
V I, Lobachik, S V, Abrosimov, V V, Zhidkov, D K, Endeka   +3 more
openaire   +2 more sources

Influence of simulated microgravity on the sympathetic response to exercise

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1997
Rats exposed to simulated conditions of microgravity exhibit reductions in aerobic exercise capacity that may be due to an impaired ability of the sympathetic nervous system (SNS) to mediate an increase in cardiac output and to redistribute blood flow.
C R, Woodman, K C, Kregel, C M, Tipton
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Plant cell in the process of the adaptation to simulated microgravity

Advances in Space Research, 1989
Analysis of structural-and-functional rearrangements in the organelles of meristematic, differentiating and differentiated cells of pea root under microgravity demonstrated certain consistencies in their manifestation, namely: a) heterogeneity of the organelles in a cell population with respect to the degree of the rearrangements; b) coincidence of a ...
openaire   +2 more sources