Results 101 to 110 of about 303,776 (293)
Advanced Biology, EarlyView.Coacervation driven by liquid‐liquid phase separation (LLPS) of biopolymers has garnered increasing attention in biology since this leads to the formation of membraneless organelles capable of performing essential yet largely unknown functions. This review highlights recent advances in coacervates (artificial condensates) composed of low‐molecular ...
Sayuri L. Higashi, Masato Ikeda
wiley +1 more source
Advanced Biology, EarlyView.Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang +6 more
wiley +1 more source
A note on $p$-adic simplicial volumes [PDF]
arXiv, 2020 We define and study generalizations of simplicial volume over arbitrary seminormed rings with a focus on $p$-adic simplicial volumes. We investigate the dependence on the prime and establish homology bounds in terms of $p$-adic simplicial volumes. As the main examples we compute the weightless and $p$-adic simplicial volumes of surfaces.
arxiv
Advanced Biology, EarlyView.The successful in situ polymerization of microtubules in giant polymer‐lipid hybrid vesicles is illustrated. The microtubules formed in the giant hybrid vesicles exhibit different morphologies including lumenal network formation and membrane association. Abstract Creating artificial cells with a dynamic cytoskeleton, akin to those in living cells, is a
Paula De Dios Andres +4 more
wiley +1 more source
Weightless: Lossy Weight Encoding For Deep Neural Network Compression [PDF]
arXiv, 2017 The large memory requirements of deep neural networks limit their deployment and adoption on many devices. Model compression methods effectively reduce the memory requirements of these models, usually through applying transformations such as weight pruning or quantization.
arxiv
Toward Design Principles for Biomolecular Condensates for Metabolic Pathways
Advanced Biology, EarlyView.Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André +3 more
wiley +1 more source
Advanced Biology, EarlyView.In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu +12 more
wiley +1 more source
High Performance Electrostatic Sensors and Actuators for LISA Proof Mass Control [PDF]
arXiv, 2001 This document contains two presentations which describe the working principles of a class of electrostatic multidimensional sensors and force actuators. The subject of the study is the search of the most effective methods for measuring the position of a cubical conducting proof mass which floats in a weightless environment.
arxiv
The Regulation of Trace Metal Elements in Cancer Ferroptosis
Advanced Biology, EarlyView.The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang +5 more
wiley +1 more source
Weyl-parallel forms, conformal products and Einstein-Weyl manifolds [PDF]
Asian Journal of Mathematics 15 (4), 499-520 (2011), 2009 Motivated by the study of Weyl structures on conformal manifolds admitting parallel weightless forms, we define the notion of conformal product of conformal structures and study its basic properties. We obtain a classification of Weyl manifolds carrying parallel forms, and we use it to investigate the holonomy of the adapted Weyl connection on ...
arxiv