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Protective effects of compound Gastrodia elata formula on the cognitive impairment induced by simulated weightlessness in mice.

Life sciences and space research
Growing evidence highlights that long-term orbital flight may lead to structural changes in brains and cognitive impairments in astronauts. However, effective strategies to counteract these effects remain limited. Compound Gastrodia elata Formula (CGEF),
Fang Chen   +10 more
semanticscholar   +1 more source

Decision making after 50 days of simulated weightlessness

Brain Research, 2009
By restricting physical activity levels, the bed rest simulation of weightlessness could be associated with changes in prefrontal cortex functioning that manifest as cognitive decrements, particularly for executive cognitive functions. We aimed to determine if performance on an executive function task was indeed affected by bed rest.
Darren M, Lipnicki   +3 more
openaire   +2 more sources

The Effects of Simulated Weightlessness on Bone Maturation*

Endocrinology, 1987
In earlier studies we showed that elevating the hind limbs of growing rats for up to 2 weeks results in a temporary cessation of bone growth in the hind limbs and a transient fall in the serum levels of 1,25-dihydroxyvitamin D. To determine whether such skeletal unloading also retards the maturation of bone, as seen in vitamin D-deprived animals, we ...
D D, Bikle   +4 more
openaire   +2 more sources

Changes of brain response induced by simulated weightlessness

Acta Astronautica, 1992
The characteristics change of brain response was studied during 15 degrees head-down tilt (HDT) comparing with 45 degrees head-up tilt (HUT). The brain responses evaluated included the EEG power spectra change at rest and during mental arithmetic, and the event-related potentials (ERPs) of somatosensory, selective attention and mental arithmetic ...
J, Wei, G, Yan, Z, Guan
openaire   +2 more sources

Skeletal abnormalities in rats induced by simulated weightlessness

Metabolic Bone Disease and Related Research, 1982
A hypokinetic model has been developed which attempts to simulate the weightlessness experienced during space flight. Male rats (approximately 130 g) were suspended from the model with a head-down tilt for a two-week period. Total mechanical unloading of the hind limbs and partial unloading of the fore limbs occurred.
T J, Wronski, E R, Morey
openaire   +2 more sources

Contributory factors to orthostatic intolerance after simulated weightlessness

Clinical Physiology, 1999
Various factors may contribute to orthostatic intolerance (OI) observed after space flights or simulated weightlessness such as bed rest experiments: individual physical and physiological factors (arterial blood pressure (BP), height), physiological changes induced by real or simulated weightlessness (hypovolaemia, increase in venous distensibility ...
A, Pavy-Le Traon   +4 more
openaire   +2 more sources

[Weightlessness or weightlessness simulation and vascular remodeling].

Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering, 2003
Weightlessness is inavoidable during spaceflight. It brings profound physiological effects on human body. Vascular remodeling is one of the important changes of cardiovascular system caused by weightlessness or simulated weightlessness. The paper summarized the studies on the effects of weightlessness or weightlessness simulation on vascular remodeling
Yong, Yue   +3 more
openaire   +1 more source

Effects of Simulated Weightlessness on Bone Mineral Metabolism

Endocrinology, 1984
Space flight and bedrest result in a negative calcium balance and osteopenia. The mechanisms underlying these events are not well understood. In particular, it is not clear whether systemic or local factors are preeminent in mediating the effects of gravity on bone mineral content.
R K, Globus, D D, Bikle, E, Morey-Holton
openaire   +2 more sources

Human Autonomic Responses to Actual and Simulated Weightlessness

The Journal of Clinical Pharmacology, 1991
Orthostatic dysfunction occurs after exposure to microgravity, and is not completely understood. The authors developed a device for stimulating carotid baroreceptors to test the hypothesis that exposure to microgravity leads to impairment of arterial baroreflex mechanisms.
D L, Eckberg, J M, Fritsch
openaire   +2 more sources

[Mechanism of cardiac atrophy under weightlessness/simulated weightlessness].

Sheng li xue bao : [Acta physiologica Sinica], 2017
Cardiac remodeling is the heart's response to external or internal stimuli. Weightlessness/simulated weightlessness leads to cardiac atrophy and heart function declining. Understanding the mechanism of cardiac atrophy under weightlessness is important to help astronaut recover from unloading-induced cardiovascular changes after spaceflight.
Guo-Hui, Zhong   +2 more
openaire   +1 more source

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