Impacts of Simulated Weightlessness by Dry Immersion on Optic Nerve Sheath Diameter and Cerebral Autoregulation [PDF]
Frontiers in Physiology, 2017 Dry immersion (DI) is used to simulate weightlessness. We investigated in healthy volunteers if DI induces changes in ONSD, as a surrogate marker of intracranial pressure (ICP) and how these changes could affect cerebral autoregulation (CA).
Marc Kermorgant +13 more
doaj +5 more sources
Objects Mental Rotation under 7 Days Simulated Weightlessness Condition: An ERP Study [PDF]
Frontiers in Human Neuroscience, 2017 During the spaceflight under weightlessness condition, human's brain function may be affected by the changes of physiological effects along with the distribution of blood and body fluids to the head.
Hui Wang +5 more
doaj +5 more sources
Placenta-Expanded Stromal Cell Therapy in a Rodent Model of Simulated Weightlessness [PDF]
Cells, 2021 Long duration spaceflight poses potential health risks to astronauts during flight and re-adaptation after return to Earth. There is an emerging need for NASA to provide successful and reliable therapeutics for long duration missions when capability for ...
Linda Rubinstein +11 more
doaj +3 more sources
Protective effects of ginsenosides on macrophages subjected to simulated weightlessness
Digital Chinese Medicine, 2023 Objective: To investigate the evolution of inflammation under conditions and the effects of ginsenosides on macrophages subjected to the simulated weightlessness, with the aim of mitigating the inflammation.
Boye Li +5 more
doaj +3 more sources
Local mapping of root orientation traits by X-ray micro-CT and 3d image analysis: A study case on carrot seedlings grown in simulated vs real weightlessness [PDF]
Plant MethodsBackground Root phenotyping is particularly challenging because of complexity and inaccessibility of root apparatus. Orientation is one of the most important architectural traits of roots and its characterization is generally addressed using multiple ...
L. Gargiulo +4 more
doaj +3 more sources
External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial [PDF]
npj Microgravity, 2023 The exact pathophysiology of the spaceflight-associated neuro-ocular syndrome (SANS) has so far not been completely elucidated. In this study we assessed the effect of acute head-down tilt position on the mean flow of the intra- and extracranial vessels.
Alessa L. Boschert +12 more
doaj +3 more sources
Fresh Gastrodia elata Blume alleviates simulated weightlessness-induced cognitive impairment by regulating inflammatory and apoptosis-related pathways [PDF]
Frontiers in Pharmacology, 2023 In aerospace medicine, the influence of microgravity on cognition has always been a risk factor threatening astronauts’ health. The traditional medicinal plant and food material Gastrodia elata Blume has been used as a therapeutic drug for neurological ...
Yiwen Zhang +10 more
doaj +3 more sources
Sensorimotor performance and haptic support in simulated weightlessness. [PDF]
Exp Brain Res, 2020 AbstractThe success of many space missions critically depends on human capabilities and performance. Yet, it is known that sensorimotor performance is degraded under conditions of weightlessness. Therefore, astronauts prepare for their missions in simulated weightlessness under water.
Weber B +3 more
europepmc +7 more sources
Cardiovascular System Under Simulated Weightlessness: Head-Down Bed Rest vs. Dry Immersion [PDF]
Frontiers in Physiology, 2020 BackgroundThe most applicable human models of weightlessness are −6° head-down bed rest (HDBR) and head-out dry immersion (DI). A detailed experimental comparison of cardiovascular responses in both models has not yet been carried out, in spite of ...
Liubov Amirova +9 more
doaj +3 more sources
Simulated weightlessness affects the expression and activity of neuronal nitric oxide synthase in the rat brain. [PDF]
Oncotarget, 2017 Spaceflight induces pathophysiological alterations in various organs. To study pathophysiological adaptations to weightlessness on the ground, the tail suspension (TS) rat model has been used to simulate the effects of weightlessness.
Yoon N, Na K, Kim HS.
europepmc +4 more sources