Numerical analysis of blood flow in the abdominal aorta under simulated weightlessness and earth conditions. [PDF]
Sci RepBlood flow through the abdominal aorta and iliac arteries is a crucial area of research in hemodynamics and cardiovascular diseases. To get in to the problem, this study presents detailed analyses of blood flow through the abdominal aorta, together with ...
Żyłka M +3 more
europepmc +4 more sources
Local mapping of root orientation traits by X-ray micro-CT and 3d image analysis: A study case on carrot seedlings grown in simulated vs real weightlessness. [PDF]
Plant MethodsBackground Root phenotyping is particularly challenging because of complexity and inaccessibility of root apparatus. Orientation is one of the most important architectural traits of roots and its characterization is generally addressed using multiple ...
Gargiulo L +4 more
europepmc +3 more sources
Placenta-Expanded Stromal Cell Therapy in a Rodent Model of Simulated Weightlessness. [PDF]
Cells, 2021 Long duration spaceflight poses potential health risks to astronauts during flight and re-adaptation after return to Earth. There is an emerging need for NASA to provide successful and reliable therapeutics for long duration missions when capability for ...
Rubinstein L +11 more
europepmc +2 more sources
Protective effects of ginsenosides on macrophages subjected to simulated weightlessness
Digital Chinese Medicine, 2023 Objective: To investigate the evolution of inflammation under conditions and the effects of ginsenosides on macrophages subjected to the simulated weightlessness, with the aim of mitigating the inflammation.
Boye Li +5 more
doaj +2 more sources
Cardiovascular System Under Simulated Weightlessness: Head-Down Bed Rest vs. Dry Immersion. [PDF]
Front Physiol, 2020 BackgroundThe most applicable human models of weightlessness are −6° head-down bed rest (HDBR) and head-out dry immersion (DI). A detailed experimental comparison of cardiovascular responses in both models has not yet been carried out, in spite of ...
Amirova L +7 more
europepmc +2 more sources
Simulated weightlessness procedure, head-down bed rest impairs adult neurogenesis in the hippocampus of rhesus macaque. [PDF]
Mol Brain, 2019 The microgravity environment in space can impact astronauts’ cognitive and behavioral activities. However, due to the limitations of research conditions, studies of biological changes in the primate brain, such as neurogenesis, have been comparatively ...
Zhang X +10 more
europepmc +2 more sources
Fresh Gastrodia elata Blume alleviates simulated weightlessness-induced cognitive impairment by regulating inflammatory and apoptosis-related pathways. [PDF]
Front Pharmacol, 2023 In aerospace medicine, the influence of microgravity on cognition has always been a risk factor threatening astronauts’ health. The traditional medicinal plant and food material Gastrodia elata Blume has been used as a therapeutic drug for neurological ...
Zhang Y +8 more
europepmc +2 more sources
Influence of Social Isolation During Prolonged Simulated Weightlessness by Hindlimb Unloading. [PDF]
Front Physiol, 2019 The hindlimb unloading (HU) model has been used extensively to simulate the cephalad fluid shift and musculoskeletal disuse observed in spaceflight with its application expanding to study immune, cardiovascular and central nervous system responses, among
Tahimic CGT +10 more
europepmc +2 more sources
External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial. [PDF]
NPJ Microgravity, 2023 The exact pathophysiology of the spaceflight-associated neuro-ocular syndrome (SANS) has so far not been completely elucidated. In this study we assessed the effect of acute head-down tilt position on the mean flow of the intra- and extracranial vessels.
Boschert AL +12 more
europepmc +2 more sources
Tapping into rhythm generation circuitry in humans during simulated weightlessness conditions. [PDF]
Front Syst Neurosci, 2015 An ability to produce rhythmic activity is ubiquitous for locomotor pattern generation and modulation. The role that the rhythmogenesis capacity of the spinal cord plays in injured populations has become an area of interest and systematic investigation ...
Solopova IA +5 more
europepmc +2 more sources