Results 101 to 110 of about 11,574,340 (406)
Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
FEBS Open Bio, EarlyView.We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo +2 more
wiley +1 more source
MedEdPublish, 2023 Lego® Serious Play® is a guided workshop in which participants construct Lego creations to represent symbolic and metaphorical ideas in response to assignments.
Pier Luigi Ingrassia +2 more
doaj
Scientific Reports, 2023 This study investigates the validity evidence of metrics used for the assessment of surgical skills for Manual Small Incision Cataract Surgery (MSICS) in a virtual reality simulator. MSICS surgery is a low-cost, low-technology cataract surgery technique,
Daniel E. Hutter +8 more
doaj +1 more source
Dissolution of Microalloying Elements in a Ladle Metallurgy Furnace
Metals, 2023 Industrial fusion of microalloying elements in steelmaking is imperative in defining and optimizing certain steel properties due to their strengthening and significant grain refinements effects at minute quantities.
Ogochukwu Queeneth Duruiheme +3 more
doaj +1 more source
Simulation of a telecommunication system using simML [PDF]
, 2000 The cost of building a new system is usually quite high and without a proper design, a mismatch might occur between the proposed system and the actual system delivered. One aspect that is important to be investigated prior to the system implementation is
Arief, Budi +2 more
core +1 more source
Robotic Simulations, Simulations of Robots
Minds and Machines, 2019 Simulation studies have been carried out in robotics for a variety of epistemic and practical purposes. Here it is argued that two broad classes of simulation studies can be identified in robotics research. The first one is exemplified by the use of robotic systems to acquire knowledge on living systems in so-called biorobotics, while the second class ...
V. Schiaffonati, DATTERI, EDOARDO
openaire +2 more sources
FEBS Open Bio, EarlyView.Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy +14 more
wiley +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
The Simulator: An Engine to Streamline Simulations [PDF]
arXiv, 2016 The simulator is an R package that streamlines the process of performing simulations by creating a common infrastructure that can be easily used and reused across projects. Methodological statisticians routinely write simulations to compare their methods to preexisting ones.
arxiv
Valuing American Options by Simulation: A Simple Least-Squares Approach
, 2001 This article presents a simple yet powerful new approach for approximating the value of American options by simulation. The key to this approach is the use of least squares to estimate the conditional expected payoff to the optionholder from continuation.
F. Longstaff, Eduardo S. Schwartz
semanticscholar +1 more source