Results 21 to 30 of about 4,573,767 (189)
AbstractThe performance of simulated annealing methods for finding a global minimum point of a function is studied.
openaire +2 more sources
Modeling survival times using frailty models [PDF]
Traditional survival models, including Kaplan Meier, Nelson Aalen and Cox regression assume a homogeneous population; however, these are inappropriate in the presence of heterogeneity.
Camilleri, Liberato+3 more
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The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Standard error estimation for EM applications related to Latent class models [PDF]
The EM algorithm is a popular method for computing maximum likelihood estimates. It tends to be numerically stable, reduces execution time compared to other estimation procedures and is easy to implement in latent class models.
Camilleri, Liberato+1 more
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Selling simulation and simulation results [PDF]
Selling simulation as a valid analysis tool is the first, and maybe the most important, step in the simulation process. Once the decision has been made to use simulation, the analyst must then be concerned with selling the ultimate results produced by the simulation.
openaire +2 more sources
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Investigating the factors which affect the performance of the EM algorithm in Latent class models [PDF]
Latent class models have been used extensively in market segmentation to divide a total market into market groups of consumers who have relatively similar product needs and preferences.
Camilleri, Liberato+3 more
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Designing Effective Simulation Games for Active Learning in Systems Engineering [PDF]
Simulation games have been an effective method of teaching, especially for Systems Engineering concepts. The hands-on activities facilitate active, experiential, and collaborative learning with fun elements.
Gupta, Nihar, Wan, Hung-da
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A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Design project planning, monitoring and re-planning through process simulation [PDF]
Effective management of design schedules is a major concern in industry, since timely project delivery can have a significant influence on a company’s profitability.
Clarkson, PJ, Wynn, DC
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