Results 41 to 50 of about 3,180,639 (313)

The SIMCO containment code applied to modeling hydrogen distribution in containments of nuclear power facilities [PDF]

open access: yesNuclear Energy and Technology, 2018
The article gives a general description of the SIMCO calculation code designed to simulate thermohydraulic and physico-chemical processes in containments of nuclear power facilities.
Vyacheslav I. Dorovskikh   +4 more
doaj   +3 more sources

Investigation of Jamming Phenomenon in a Direct Reduction Furnace Pellet Feed System Using the Discrete Element Method

open access: yesDynamics, 2023
A continuous iron ore pellet feed system for a direct reduction ironmaking furnace is reportedly jamming in a hopper above the furnace, where a counterflowing gas seals off the furnace flue gas.
John G. Rosser   +3 more
doaj   +1 more source

Simulations in coalgebra

open access: yesTheoretical Computer Science, 2003
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jacobs, B.P.F., Hughes, J.
openaire   +4 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Correction to: COVID-19 pandemic preparation: using simulation for systems-based learning to prepare the largest healthcare workforce and system in Canada

open access: yesAdvances in Simulation, 2021
An amendment to this paper has been published and can be accessed via the original article.
Mirette Dubé   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Robotic Simulations, Simulations of Robots

open access: yesMinds and Machines, 2019
Simulation studies have been carried out in robotics for a variety of epistemic and practical purposes. Here it is argued that two broad classes of simulation studies can be identified in robotics research. The first one is exemplified by the use of robotic systems to acquire knowledge on living systems in so-called biorobotics, while the second class ...
Edoardo Datteri, Viola Schiaffonati
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

DIY: Creating Performance Assessments that Measure Up!

open access: yesMedEdPORTAL, 2014
Introduction The demand for simulation educators to become involved in high stakes performance assessment is growing rapidly. The ability to construct reliable and valid performance assessments, and to evaluate those already available, is necessary in ...
Ann Willemsen-Dunlap   +5 more
doaj   +1 more source

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