Results 41 to 50 of about 4,573,767 (189)

Sensornet checkpointing: enabling repeatability in testbeds and realism in simulations [PDF]

open access: yes, 2009
When developing sensor network applications, the shift from simulation to testbed causes application failures, resulting in additional time-consuming iterations between simulation and testbed. We propose transferring sensor network checkpoints between
Dunkels, Adam   +5 more
core   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Simulation heat transfer fluids efficiency and molten salts in heat collecting elements in concentrating solar power [PDF]

open access: yes, 2016
Postprint (published ...
Amante García, Beatriz   +3 more
core  

Robotic Simulations, Simulations of Robots

open access: yesMinds and Machines, 2019
Simulation studies have been carried out in robotics for a variety of epistemic and practical purposes. Here it is argued that two broad classes of simulation studies can be identified in robotics research. The first one is exemplified by the use of robotic systems to acquire knowledge on living systems in so-called biorobotics, while the second class ...
V. Schiaffonati, DATTERI, EDOARDO
openaire   +2 more sources

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Numerical Simulation on Shoreline Change in Western Region of Badung Regency, Bali, Indonesia [PDF]

open access: yes, 2014
Shoreline change is considered the most dynamic processes in coastal region. Coastal erosion is a global problem where 70% beaches around the world are recessional. Almost all coastal area in Bali is potential to suffer from erosion.
Asai, K. (Koji)   +1 more
core  

Reproducible computational biology experiments with SED-ML - The Simulation Experiment Description Markup Language [PDF]

open access: yes, 2011
Background: The increasing use of computational simulation experiments to inform modern biological research creates new challenges to annotate, archive, share and reproduce such experiments.
Adams, Richard   +10 more
core   +5 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Stress and Strain in Flat Piling of Disks

open access: yes, 2003
We have created a flat piling of disks in a numerical experiment using the Distinct Element Method (DEM) by depositing them under gravity. In the resulting pile, we then measured increments in stress and strain that were associated with a small decrease ...
Arthur J. R. F.   +17 more
core   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

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