Results 41 to 50 of about 6,077,636 (282)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Investigation of Jamming Phenomenon in a Direct Reduction Furnace Pellet Feed System Using the Discrete Element Method

open access: yesDynamics, 2023
A continuous iron ore pellet feed system for a direct reduction ironmaking furnace is reportedly jamming in a hopper above the furnace, where a counterflowing gas seals off the furnace flue gas.
John G. Rosser   +3 more
doaj   +1 more source

Distributed agent-based building evacuation simulator [PDF]

open access: yes, 2012
The optimisation of the evacuation of a building plays a fundamental role in emergency situations. The behaviour of individuals, the directions that civilians receive, and the actions of the emergency personnel, will affect the success of the operation ...
Filippoupolitis, Avgoustinos   +6 more
core  

Sensornet checkpointing: enabling repeatability in testbeds and realism in simulations [PDF]

open access: yes, 2009
When developing sensor network applications, the shift from simulation to testbed causes application failures, resulting in additional time-consuming iterations between simulation and testbed. We propose transferring sensor network checkpoints between
Dunkels, Adam   +5 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Numerical simulation of convective airflow in an empty room [PDF]

open access: yes, 2011
Numerical simulation of airflow inside an empty room has been carried out for a forced convection, a natural convection and a mixed convection respectively, by using a computational fluid dynamics approach of solving the Reynolds-averaged Navier-Stokes ...
Horikiri, Kana, Yao, Jun, Yao, Yufeng
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The SIMCO containment code applied to modeling hydrogen distribution in containments of nuclear power facilities [PDF]

open access: yesNuclear Energy and Technology, 2018
The article gives a general description of the SIMCO calculation code designed to simulate thermohydraulic and physico-chemical processes in containments of nuclear power facilities.
Vyacheslav I. Dorovskikh   +4 more
doaj   +3 more sources

Design project planning, monitoring and re-planning through process simulation [PDF]

open access: yes, 2009
Effective management of design schedules is a major concern in industry, since timely project delivery can have a significant influence on a company’s profitability.
Clarkson, PJ, Wynn, DC
core  

Simulated annealing simulated

open access: yesComputers & Mathematics with Applications, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

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