Results 71 to 80 of about 3,634,315 (300)
Analysis, Simulation and Control of a New Measles Epidemic Model [PDF]
, 2019 In this paper the problem of modeling and controlling the measles epidemic spread is faced. A new model is proposed and analysed; besides the categories usually considered in measles modeling, the susceptible, the exposed, the infected, the removed and,
DI GIAMBERARDINO, Paolo +1 more
core +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Shuitu Baochi Xuebao[Objective] Soil erosion is a prominent ecological problem in southwestern Hubei Province. A reasonable assessment of the vulnerability of soil erosion in this area and exploration of its driving mechanisms are prerequisites for effective soil and water ...
YANG Yanpan +6 more
doaj +1 more source
Sensitivity Analysis of Simulation Models [PDF]
SSRN Electronic Journal, 2009 This contribution presents an overview of sensitivity analysis of simulation models, including the estimation of gradients. It covers classic designs and their corresponding (meta)models; namely, resolution-III designs including fractional-factorial two-level designs for first-order polynomial metamodels, resolution-IV and resolution-V designs for ...
openaire +5 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Post-Supernatural Cultures: There and Back Again
Secularism and Nonreligion, 2020 The abandonment of supernatural religious beliefs and rituals seems to occur quite easily in some contexts, but post-supernaturalist cultures require a specific set of conditions that are difficult to produce and sustain on a large scale and thus are ...
Wesley J. Wildman +4 more
doaj +1 more source
Application of Subset Simulation to Seismic Risk Analysis [PDF]
, 2002 This paper presents the application of a new reliability method called Subset Simulation to seismic risk analysis of a structure, where the exceedance of some performance quantity, such as the peak interstory drift, above a specified threshold level is ...
Au, Siu-Kui, Beck, James L.
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source