Results 71 to 80 of about 672,616 (313)
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Design project planning, monitoring and re-planning through process simulation
, 2009 Effective management of design schedules is a major concern in industry, since timely project delivery can have a significant influence on a company’s profitability.
P John Clarkson, David C Wynn
core
On the design of hybrid simulation models, focussing on the agent-based system dynamics combination [PDF]
, 2014 ©Cranfield University, 2014There is a growing body of literature reporting the application of hybrid simulations to inform decision making. However, guidance for the design of such models, where the output depends upon more than one modelling paradigm ...
Swinerd, Chris
core
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
GMS Journal for Medical EducationBackground: Simulation-based medical education is increasingly important in postgraduate training, yet the comparative merits of in-house vs. society-accredited courses are still not well understood.
Abramovich, Igor +4 more
doaj +1 more source
International Journal of Naval Architecture and Ocean Engineering, 2017 Naval ships are assigned many and varied missions. Their performance is critical for mission success, and depends on the specifications of the components. This is why performance analyses of naval ships are required at the initial design stage. Since the
Dong-Hoon Jeong +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Modelling iteration in engineering design
, 2007 This paper examines design iteration and its modelling in the simulation of New Product Development (NPD) processes. A framework comprising six perspectives of iteration is proposed and it is argued that the importance of each perspective depends upon ...
Eckert, C. M. +2 more
core
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source