Results 51 to 60 of about 672,616 (313)
Glucose Sensor Design Based on Monte Carlo Simulation
BiosensorsContinuous glucose monitoring based on the minimally invasive implantation of glucose sensor is characterized by high accuracy and good stability.
Gang Xue +4 more
doaj +1 more source
GPS L1 Signal Simulation and Interface Design
Gazi Üniversitesi Fen Bilimleri Dergisi, 2019 The use of satellite-based positioning systems such as Global Positioning System (GPS) has become increasingly popular and these systems are becoming more and more common in all transportation modes, especially in air transportation.
Ahmet Esat SÜZER, Hakan OKTAL
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Conceptual Design of a Hydraulic Valve Train System
Acta Polytechnica, 2001 Variable valve train systems have been brought into focus during recent years as a means to decrease fuel consumption in tomorrow's combustion engines.
J. Pohl +3 more
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A quantitative model of hierarchical product design
Design ScienceAnalysing hierarchical design processes is difficult due to the technical and organizational dependencies spanning over multiple levels. The V-Model of Systems Engineering considers multiple levels. It is, however, not quantitative.
Ferdinand Wöhr +3 more
doaj +1 more source
Simulation Design of A General Purpose Microprocessor Based on FPGA [PDF]
Engineering and Technology Journal, 2010 A General purpose microprocessor is one having the capability to execute the usual set of instructions like arithmetic, logic, branching and other control instructions.
Sabah Abdul-Hassan
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Design and discrete event simulation of power and free handling systems [PDF]
, 1997 Effective manufacturing systems design and implementation has become increasingly critical, with the reduction in manufacturing product lead times, and the subsequent influence on engineering projects.
Lynn, Jeffrey Alexander
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