Results 61 to 70 of about 2,758,037 (275)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Correlation functions and computer simulations

open access: yesNuclear Physics B, 1981
If the equilibrium properties of a statistical system are obtained by solving numerically the associated Langevin equation describing the approach to equilibrium, the connected correlation functions can be computed directly with small effort and high precision.
openaire   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Interpolative Rus-Reich-Ćirić Type Contractions via Simulation Functions

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2019
In this paper, we introduce the notion of interpolative Rus-Reich-Ćirić type 𝒵- contractions in the setting of complete metric space. We also consider some immediate consequences of our main results.
Karapınar Erdal, Agarwal Ravi P.
doaj   +1 more source

Acceleration of the SPADE Method Using a Custom-Tailored FP-Growth Implementation

open access: yesFrontiers in Neuroinformatics, 2021
The SPADE (spatio-temporal Spike PAttern Detection and Evaluation) method was developed to find reoccurring spatio-temporal patterns in neuronal spike activity (parallel spike trains).
Florian Porrmann   +8 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

A System-on-Chip Based Hybrid Neuromorphic Compute Node Architecture for Reproducible Hyper-Real-Time Simulations of Spiking Neural Networks

open access: yesFrontiers in Neuroinformatics, 2022
Despite the great strides neuroscience has made in recent decades, the underlying principles of brain function remain largely unknown. Advancing the field strongly depends on the ability to study large-scale neural networks and perform complex ...
Guido Trensch   +4 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

odMLtables: A User-Friendly Approach for Managing Metadata of Neurophysiological Experiments

open access: yesFrontiers in Neuroinformatics, 2019
An essential aspect of scientific reproducibility is a coherent and complete acquisition of metadata along with the actual data of an experiment. The high degree of complexity and heterogeneity of neuroscience experiments requires a rigorous management ...
Julia Sprenger   +11 more
doaj   +1 more source

Stochastic wave-function simulation of two-time correlation functions [PDF]

open access: yesJournal of Modern Optics, 1999
17 pages, 3 EPS ...
Felbinger, Timo   +1 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy