Results 61 to 70 of about 5,438,311 (249)
Loss functions, utility functions and Bayesian sample size determination. [PDF]
, 2011 PhDThis thesis consists of two parts. The purpose of the first part of the research is to obtain Bayesian sample size determination (SSD) using loss or utility function with a linear cost function. A number of researchers have studied the Bayesian SSD
Islam, A. F. M. Saiful
core +4 more sources
, 1980 This study represents an attempt to measure the effects of participating in a business simulation on the attitudes of the participants relative to a number of managerial functions.
Decker, Ronald L.
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Journal of Agricultural and Resource Economics, 2000 Recently developed techniques are adapted and combined for the modeling and simulation of crop yields and prices that can be mutually correlated, exhibit heteroskedasticity or autocorrelation, and follow nonnormal probability density functions.
Octavio A. Ramirez, Romeo Sosa
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Epistemology of modeling and simulation
, 2013 While ontology deals with the question of being or existence, epistemology deals with the question of gaining knowledge. This panel addresses the challenge of how we gain knowledge from modeling and simulation.
Tolk, A. +17 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Towards virtual validation of distributed functions
, 2022 Art.153021Continuous development of software functions using software-in-the-loop (SiL) simulations up to their virtual validation or virtual release are key enablers for new technologies of autonomous and connected mobility.
Mikelsons, Lars +4 more
core +1 more source
Quantum wave simulation with sources and loss functions
Physical Review ResearchWe present a quantum algorithmic framework for simulating linear, anti-Hermitian (lossless) wave equations in heterogeneous, anisotropic, and time-independent media.
Cyrill Bösch +4 more
doaj +1 more source
Simulation of stationary, non-normal random process
Vietnam Journal of Mechanics, 1992 Simulation of stationary random processes specified by spectral density function and NonNormal probability density function has been rarely studied, though these processes are often met in both theory and practice.
Nguyen Cao Menh, Tran Duong Tri
doaj +1 more source