Results 61 to 70 of about 15,112,343 (251)

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Theoretical study on the electronic properties and multiorbital models of La3Ni2O7 thin films on SrLaAlO4 (001)

AAPPS Bulletin
The realization of high-temperature superconductivity in La3Ni2O7 thin films under ambient pressure has triggered a fundamental inquiry into the microscopic origin of the superconducting ground state—specifically, whether the requisite charge carrier ...
Guanlin Li, Cui-Qun Chen, Haoliang Shi, Zhengtao Liu, Hao Ma, Fubo Tian, Dao-Xin Yao, Defang Duan   +7 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Study on the simulation of simultaneous full AT-POLINSAR

The Journal of Engineering, 2019
With the maturity of the instantaneous full-polarisation measurement, the instantaneous full-polarimetric system is becoming an important development direction of the polarimetric synthetic aperture radar (POLSAR); however, as an important research ...
Peng Zhang, Penghao Yan, Jialun Yao, Xuan Zhao, Qi Zhang, Tao Liu   +5 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Metallic Hydrogen Ligand Compounds: A Potential Route to Superconducting Metallic Hydrogen at Ambient Pressure

Gaoya wuli xuebao
Metallic hydrogen, with its properties including room-temperature superconductivity and quantum fluidity, is known as the holy grail of high-pressure physics.
Zihan ZHANG, Defang DUAN, Tian CUI
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Semi-Markov Model of MASS Voyage [PDF]

TransNav
The paper presents the readiness/safety model for the sea voyage of Maritime Autonomous Surface Ship (MASS), based on Semi-Markov process. The states of MASS during the voyage were defined as triplets of intentional type of MASS operations, reliability ...
Teresa Abramowicz-Gerigk, Zbigniew Burciu, Joanna Soszynska-Budny, Adam Weintrit   +3 more
doaj   +1 more source

Advanced Simulation-Based Methods for Optimal Stopping and Control

, 2018
This is an advanced guide to optimal stopping and control, focusing on advanced Monte Carlo simulation and its application to finance. Written for quantitative finance practitioners and researchers in academia, the book looks at the classical simulation ...
Schoenmakers, John G. M., Denis Belomestny, John Schoenmakers, Belomestny, Denis   +3 more
core   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source