Results 51 to 60 of about 15,112,343 (251)

Selected Problems of Sensitivity and Reliability of a Jack-Up Platform

Polish Maritime Research, 2018
The paper deals with sensitivity and reliability applications to numerical studies of an off-shore platform model. Structural parameters and sea conditions are referred to the Baltic jack-up drilling platform. The sudy aims at the influence of particular
Rozmarynowski Bogdan, Mikulski Tomasz
doaj   +1 more source

Simulation-based optimization of agent scheduling in multiskill call centers.

, 2007
We examine and compare simulation-based algorithms for solvingthe agent scheduling problem in a multiskill call center.This problem consists in minimizing the total costs of agents underconstraints on the expected service level per call type,per period ...
Gendreau, M., Athanassios N. Avramidis, Ornella Pisacane, Pisacane, O., L'Ecuyer P, Gendreau, Michel, Avramidis, Athanassios N., Michel Gendreau, L'Ecuyer, Pierre, PISACANE, ORNELLA, Pierre L’Ecuyer, L'Ecuyer, P., Avramidis A. N, Gendreau M, Avramidis, A.N.   +14 more
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

CFD analysis of the main operating parameters for a complete braking friction system under transient working conditions

International Journal of Thermofluids
A braking system represents a very complex physical system to be properly modelled since it involves the solution of multiphase flow and thermal distribution and multi-body motions under dynamic operating conditions.
F. Orlandi, C. De Marco, S. Meleti, A. Manian, M. Milani, L. Montorsi   +5 more
doaj   +1 more source

Simulation-based Estimation Methods for Financial Time Series Models [PDF]

This chapter overviews some recent advances on simulation-based methods of estimating financial time series models that are widely used in financial economics.
Jun Yu
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Simulation-based Education: A Vital Inclusion for Competency Building in Ayurveda Education [PDF]

Journal of Clinical and Diagnostic Research
Dear Editor, Simulation-Based Learning (SBL) provides learners with realistic, immersive learning experiences that closely mimic real-world clinical situations, making it a valuable tool for training and evaluation [1].
Seema H Thakare, Sumant Pande
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Sequestration of helium and xenon via iron-halide compounds in early Earth

Matter and Radiation at Extremes
The terrestrial abundance anomalies of helium and xenon suggest the presence of deep-Earth reservoirs of these elements, which has led to great interest in searching for materials that can host these usually unreactive elements.
Jurong Zhang, Hanyu Liu, Changfeng Chen, Yanming Ma   +3 more
doaj   +1 more source