Results 51 to 60 of about 27,508,585 (286)
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Practitioners' perception of the impacts of virtual reality on discrete-event simulation [PDF]
This paper presents the results from surveying simulation practitioners from industry and academics who have used 2D or 3D software applications for Discrete-Event Simulation (DES) projects.
Akpan, J I, Brooks, R J
core +4 more sources
Introduction: Simulation-based learning (SBL) is a practical and efficient learning method that involves the replacement of a portion of clinical education with quality simulation experiences. It has been utilised in various countries, such as the United
Mitsumi Masuda +2 more
doaj +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Problem of describing the function of a GPR source
In this paper, we consider the problem of determining the source h(t)δ(x) of electromagnetic waves from GPR data. The task of electromagnetic sensing is to find the pulse characteristic of the medium r(t) and consists in calculating the response of the ...
S.I. Kabanikhin +4 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Performance improvement of single- and multi-frequency direct sampling methods in microwave imaging
Recently, it turned out that application of multiple frequency direct sampling method (DSM) does not guarantee a good result in microwave imaging. Here we propose and numerically demonstrate alternative single- and multi-frequency indicator functions of ...
Won-Kwang Park
doaj +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
On developing efficient applications using conservative distributed simulation paradigm
This paper aims to present, using a set of guidelines, how to apply the conservative distributed simulation paradigm (CMB protocol) to develop efficient applications.
Spolon, Roberta +3 more
core +3 more sources
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

