Results 71 to 80 of about 247,099 (269)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Evaluation of Virtual Reality Snowplow Simulator Training, January 2007
, 2007 Each winter, Iowa Department of Transportation (Iowa DOT) maintenance operators are responsible for plowing snow off federal and state roads in Iowa. Drivers typically work long shifts under treacherous conditions.
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Software for Explicitly Parallel Memory-Centric Processor Architect
Proceedings of the International Conference on Applied Innovations in IT, 2015 Advances in computer memory technology justify research towards new and different views on computer organization. This paper proposes a novel memory-centric computing architecture with the goal to merge memory and processing elements in order to provide ...
Goce Dokoski +3 more
doaj +1 more source
Control of a Dynamic Driving Simulator: Time-Variant Motion Cueing Algorithms and Prepositioning
, 2006 This thesis mainly addresses the task to provide the driver of a dynamic driving simulator with the same motion cues as would occur in reality. The DLR Driving Simulator, which is the subject matter of this thesis, uses a hexapod motion platform to ...
Weiß, Cornelius
core
Development and validation of a simulator for wireless data acquisition in gas turbine engine testing [PDF]
, 2013 Owing to its cable-free deployment, wireless sensor networks (WSNs) have drawn great attention as a new technique for industrial data acquisition. However, the harsh environment of the gas turbine engine provides a number of challenges to deployment of ...
Atkinson, Robert +21 more
core +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source