Results 111 to 120 of about 15,260 (213)
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Mitigating simultaneity bias in seaport efficiency measurement [PDF]
Kenneth Løvold Rødseth, Timo Kuosmanen, Rasmus Bøgh Holmen, Mitigating simultaneity bias in seaport efficiency measurement, Transportation Research Part A: Policy and Practice, Volume 192, 2025, 104333, ISSN 0965-8564,Seaport efficiency measurement is ...
Kuosmanen, Timo +2 more
core +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Prosody of focus in Turkish Sign Language
Prosodic realization of focus has been a widely investigated topic across languages and modalities. Simultaneous focus strategies are intriguing to see how they interact regarding their functional and temporal alignment.
Serpil Karabüklü, Aslı Gürer
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Teoria fenomenológica do processo de relaxação dielétrica
O objetivo deste trabalho é introduzir o conceito de não simultaneidade entre causa e efeito, o que não é muito comum em diversos problemas de física e biologia, mostrando como tratá-los e verificando em que condições os dois modelos conduzem a ...
Renê Robert
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Crossmodal simultaneity is not transitive
Machulla TK, Di Luca M, Ernst MO. Crossmodal simultaneity is not transitive. Presented at the 10th Tübinger Wahrnehmungskonferenz (TWK 2007)
Machulla, T. +5 more
core

